[HTML][HTML] Wnt signaling in triple-negative breast cancer

SÖG Pohl, N Brook, M Agostino, F Arfuso, AP Kumar… - Oncogenesis, 2017 - nature.com
breast cancer, known as triple-negative breast cancer (TNBC), demonstrates dysregulation
in canonical and non-canonical Wnt signalingWnt signaling, as well as Wnt signaling

[HTML][HTML] Wnt signaling in triple negative breast cancer is associated with metastasis

N Dey, BG Barwick, CS Moreno, M Ordanic-Kodani… - BMC cancer, 2013 - Springer
… ) tumor specimens from two breast cancer cohorts. Our data, together with meta-analysis of
previous breast cancer microarray studies, indicate Wnt pathwayWnt/β-catenin signaling

[HTML][HTML] Triple-negative breast cancer: understanding Wnt signaling in drug resistance

P Merikhian, MR Eisavand, L Farahmand - Cancer cell international, 2021 - Springer
… Based on this brief preface, here, we review the role of Wnt signaling in mechanisms of …
signaling pathways and the Wnt pathway and finally suggest how multi-targeting of these tumor-…

The wnt/β‐catenin signaling pathway: A potential therapeutic target in the treatment of triple negative breast cancer

TD King, MJ Suto, Y Li - Journal of cellular biochemistry, 2012 - Wiley Online Library
… Recent studies indicate that Wnt/β-catenin signaling is … of the Wnt/β-catenin signaling pathway
in breast cancer and provide evidence indicating that the Wnt/β-catenin signaling pathway

[HTML][HTML] Wnt signaling blockage inhibits cell proliferation and migration, and induces apoptosis in triple-negative breast cancer cells

B Bilir, O Kucuk, CS Moreno - Journal of translational medicine, 2013 - Springer
Wnt signaling pathway-associated genes in basal-like 2 and mesenchymal subtypes of TNBC.
In this study, we investigated the potential of Wnt pathwayWnt pathway in breast cancer

Wnt signaling in triple-negative breast cancers: Its roles in molecular subtyping and cancer cell stemness and its crosstalk with non-coding RNAs

X Yang, D Cao, W Ma, S Gao, G Wen, J Zhong - Life Sciences, 2022 - Elsevier
Wnt signaling in various contents of TNBCs, regarding to the molecular subtyping of TNBCs,
breast cancer … that targeting cancer stemness through modulating the Wnt signaling may be …

[HTML][HTML] WNT signaling modulates PD-L1 expression in the stem cell compartment of triple-negative breast cancer

L Castagnoli, V Cancila, SL Cordoba-Romero, S Faraci… - Oncogene, 2019 - nature.com
… the relevant need to increase cancer cell immunogenicity, we … signaling pathway. To achieve
this goal, our research provided evidence that WNT signaling dysfunction impacted tumor

[HTML][HTML] Dual PI3K and Wnt pathway inhibition is a synergistic combination against triple negative breast cancer

JP Solzak, RV Atale, BA Hancock, AL Sinn… - … breast cancer, 2017 - nature.com
… -PI3K inhibition in triple negative breast cancers results in marked activation of the Wnt-pathway. …
WNT974(WNT-pathway), we demonstrate significant in vitro and in vivo synergy against …

[HTML][HTML] Differential activation of Wnt-β-catenin pathway in triple negative breast cancer increases MMP7 in a PTEN dependent manner

N Dey, B Young, M Abramovitz, M Bouzyk, B Barwick… - PloS one, 2013 - journals.plos.org
tumor cells of Triple Negative subset of Breast Cancer (TNBC) deregulate pathways of signal
… MMP7, a transcriptional target of Wnt-β-catenin signature pathway in TNBC is associated to …

[HTML][HTML] FZD7 has a critical role in cell proliferation in triple negative breast cancer

L Yang, X Wu, Y Wang, K Zhang, J Wu, YC Yuan… - Oncogene, 2011 - nature.com
… Our findings suggest that FZD7-involved canonical Wnt signaling pathway is essential for
tumorigenesis of TNBC, and thus, FZD7 shows promise as a biomarker and a potential …