products and pharmaceuticals and development of efficient methods to construct this key
motif is of vital importance. Yb (OTf) 3-catalyzed addition of 2-or 4-methyl azaarenes to
isatins via CH functionalization was developed. Moderate to good yields were obtained for
various isatins and azaarenes. This method provides rapid protocol for the synthesis of
biologically important azaarene-substituted 3-hydroxy-2-oxindoles in one step. The success …