… Advances in detection methods and development of dedicated platforms and methylation
arrays resulted in an explosion of information on aberrantly methylated sequences linking …

… In conclusion, we examined the aberrant promoter methylation status in serum DNA and
showed the usefulness of this approach as a tool for detection of lung cancer in patients …

… Methylation-specific PCR (MSP) is most often used for detecting aberrant methylation of a
CpG … Although the MSP is appropriate for detecting a few cell-free DNA molecules from a …

… /or risk was validated by detection of this change in … , aberrant methylation of the p16 gene,
can be an early event in lung cancer and may constitute a new biomarker for early detection …

… Clinical assay formats to analyze aberrantly methylated cell free DNA targets in cancer …
Following bisulfite conversion, specific DNA regions that are aberrantly methylated in cancer …

… Therefore, we now turn to pointing out the aberrantly methylated genes detected by liquid …
P) were found to be aberrantly methylated in most of the relevant studies we analyzed. …

… We first determined the frequency of aberrant methylation of … -throughput DNA methylation
assay (quantitative methylation-… for the presence of four methylated genes. Samples were …

… Regarding mammography, with a sensitivity of >70% and a specificity of >85%, a reliable
biomarker panel for early detection of breast cancer in cfDNA need to reach comparable values…

… , we set out to detect aberrant methylation of the p16 … aberrant methylation in serum and
clinicopathological findings to assess the diagnostic value of this marker for the early detection of …

… We provide evidence that aberrant methylation of TSGs in samples of induced sputum is
a useful tool for early diagnostic of lung diseases (LC and COPD) in smoker subjects. …