Accelerated longitudinal decline of aerobic capacity in healthy older adults

JL Fleg, CH Morrell, AG Bos, LJ Brant, LA Talbot… - Circulation, 2005 - Am Heart Assoc
… an accelerated decline in peak V̇o 2 across age decades by the present mixed-effects
prediction model, our median follow-up period of 7.9 years is short relative to the adult aging …

Accelerated decline in white matter microstructure in subsequently impaired older adults and its relationship with cognitive decline

AT Shafer, OA Williams, E Perez, Y An… - Brain …, 2022 - academic.oup.com
decline in verbal fluency, processing speed and mini-mental state examination. Accelerated
regional white matter microstructural decline … is related to domain-specific cognitive decline. …

Association between accelerated multimorbidity and age‐related cognitive decline in older baltimore longitudinal study of aging participants without dementia

E Fabbri, Y An, M Zoli, T Tanaka… - Journal of the …, 2016 - Wiley Online Library
… that older adults with accelerated accumulation of multimorbidity tend to have accelerated
worsening of … In conclusion, accelerated deterioration in physical health is associated with …

[HTML][HTML] Early detection of accelerated aging and cellular decline (AACD): A consensus statement

M Cesari, A Cherubini, JM Guralnik, A Beresniak… - Experimental …, 2021 - Elsevier
… Although many older adults with frailty have multimorbidity, the majority of people with …
injuries in healthier middle-aged or older adults. They suggested evaluating recovery from wound …

Accelerated long-term forgetting in healthy older adults predicts cognitive decline over 1 year

AR Wearn, E Saunders-Jennings, V Nurdal… - Alzheimer's Research & …, 2020 - Springer
… We show that a test of accelerated long-term forgetting over 4 weeks can predict cognitive
decline in healthy older people where traditional tests of delayed recall cannot. Accelerated

Gradient and Acceleration of Decline in Physical and Cognitive Functions in Older Adults: A Disparity Analysis

EH Ip, SH Chen, WJ Rejeski… - The Journals of …, 2022 - academic.oup.com
… We also examined changes in rates of decline with time—that is, acceleration. Acceleration
was measured because only knowing the average rate of decline may limit understanding of …

[HTML][HTML] Accelerated aging in older cancer survivors

MS Sedrak, JL Kirkland, T Tchkonia… - Journal of the American …, 2021 - ncbi.nlm.nih.gov
… steeper declines in grip strength and gait speed compared to cancer-free older adults. The
… of cancer and aging appear to accelerate the onset and progression of functional decline. …

Does abdominal obesity accelerate muscle strength decline in older adults? Evidence from the English Longitudinal Study of Ageing

DHT de Carvalho, S Scholes, JLF Santos… - The Journals of …, 2019 - academic.oup.com
… To the best of our knowledge, this is the first longitudinal study to investigate whether abdominal
obesity accelerates muscle strength decline among older adults over a period of 8 years …

Age-accelerated cognitive decline in asymptomatic adults with CSF β-amyloid

LR Clark, SE Berman, D Norton, RL Koscik, E Jonaitis… - Neurology, 2018 - AAN Enterprises
… For example, if a trial is enrolling older adults, it may be more optimal to choose a list-learning
memory measure since it would be expected to decline more rapidly in older adults with …

Reverse geroscience: how does exposure to early diseases accelerate the age‐related decline in health?

RA Kohanski, SG Deeks, C Gravekamp… - Annals of the New …, 2016 - Wiley Online Library
… incidence in adults age 65 years and older between 2010 and … in younger adults, rather
than in older adults who are the … accelerated aging, with older adults at particular risk.21-24 …