Toll-like receptor 2 acts as a natural innate immune receptor to clear amyloid β1–42 and delay the cognitive decline in a mouse model of Alzheimer's disease

KL Richard, M Filali, P Préfontaine… - Journal of …, 2008 - Soc Neuroscience
… The lack of TLR2 in our model of AD results in an accelerated spatial and contextual
memory deficits. These data suggest that TLR2 play an important role in memory formation. …

The theory of bipolar disorder as an illness of accelerated aging: implications for clinical care and research

LB Rizzo, LG Costa, RB Mansur, W Swardfager… - Neuroscience & …, 2014 - Elsevier
… stress imbalance, amyloid metabolism, immunological deregulation, immunosenescence,
neurotrophic deficiencies and telomere shortening) converge on a model of accelerated aging …

Renascence after post-mortem: the choice of accelerated repeat entrepreneurship

M Guerrero, I Peña-Legazkue - Small Business Economics, 2019 - Springer
… In this study, we find that favorable spatial contexts trigger the choice of accelerated
repeat entrepreneurship. It is worth noting that the effect of experiential capital on repeat …

Disruption of sonic hedgehog signaling accelerates age-related neurogenesis decline and abolishes stroke-induced neurogenesis and leads to increased anxiety …

J Wang, K Ware, A Bedolla, E Allgire… - Translational stroke …, 2022 - Springer
… Results from our challenging BM or CFC tests also showed no spatial or contextual fear
memory impairment in Smo cKO mice. Based on our IHC analysis, a severe reduction of DCX+ …

Accelerating urban sprawl in depopulating regions: a scenario analysis for the Elbe River Basin

J Hoymann - Regional Environmental Change, 2011 - Springer
… that consider two processes, accelerated urban sprawl in growth … The Land Use Scanner,
a spatially explicit land use change … by regional population declines in peripheral regions. A …

[PDF][PDF] Slow innovation in Europe's peripheral regions: Innovation beyond acceleration

H Mayer - Schlüsselakteure Reg. Welche Perspekt. Bietet Entrep …, 2020 - core.ac.uk
… However, in the context of peripheral regions, this additional dimension of ‘slowness’ … a
space where economic actors can be innovative without pressures from the modern, accelerated

Human acceleration of animal and plant extinctions: A Late Pleistocene, Holocene, and Anthropocene continuum

TJ Braje, JM Erlandson - Anthropocene, 2013 - Elsevier
… of human geographic expansion and accelerating technological developments over the
last … We explore the deep history of anthropogenic extinctions, trace the accelerating loss of …

Accelerating decline of wildfires in China in the 21st century

C Lian, C Xiao, Z Feng, Q Ma - Frontiers in Forests and Global …, 2024 - frontiersin.org
… In addition, a 0.25 × 0.25 grid was created in this study to analyze the spatial characteristics
… , we consider the spatial and temporal distribution of wildfires in China in terms of spatial and …

Decline of speech understanding and auditory thresholds in the elderly

PL Divenyi, PB Stark, KM Haupt - The Journal of the Acoustical Society …, 2005 - pubs.aip.org
… sentence context effect; SPSpat: average scores for spatially … a decline of central function
with age—beyond the decline of peripheral function—plays a role in the accelerating decline

Shrinking cities in Australia, Japan, Europe and the USA: From a global process to local policy responses

C Martinez-Fernandez, T Weyman, S Fol, I Audirac… - Progress in …, 2016 - Elsevier
… with urban decline would have been normally considered a socio-spatial manifestation of an
… producing unprecedented demographic change and the acceleration of an ageing society. …