Epigallocatechin gallate from green tea effectively blocks infection of SARS-CoV-2 and new variants by inhibiting spike binding to ACE2 receptor

J Liu, BH Bodnar, F Meng, AI Khan, X Wang, S Saribas… - Cell & bioscience, 2021 - Springer
… S protein and ACE2. While these independent and preliminary reports support our finding
that green tea has anti-SARS-CoV-2 activity, it remains to be determined whether green tea or …

[HTML][HTML] Therapeutic approach against 2019-nCoV by inhibition of ACE-2 receptor

G Kumar, D Kumar, NP Singh - Drug research, 2021 - thieme-connect.com
green tea twice a day (boil 2 gm dry leaf of green tea along with 0.25 gm Black pepper in
100 ml water). After introducing this dose to the patient, take 2.5 gm freshly prepared sun flower …

[HTML][HTML] GB-2 inhibits ACE2 and TMPRSS2 expression: In vivo and in vitro studies

CY Wu, YS Lin, YH Yang, LH Shu, YC Cheng… - Biomedicine & …, 2020 - Elsevier
… Angiotensin converting enzyme 2 (ACE2) receptor can bind to spike protein of SARS-CoV-2.
Then, the spike protein of SARS-CoV-2 can be cleaved and activated by transmembrane …

[PDF][PDF] Interaction Between Ace 2 and SARS-CoV-2, And Use of Egcg And Theaflavin to Treat Covid 19 in Initial Phases

SS Imam, ST Imam, K Mdwasifathar… - Int. J. Curr. Pharm …, 2022 - academia.edu
ACE 2 receptor site and transfers the viral genome within the host cell. The interaction between
SARS-Cov19's S glycoprotein (spikes) and the body's ACE 2 receptor site is … in green tea, …

The green tea catechin epigallocatechin gallate inhibits SARS-CoV-2 infection

L Henss, A Auste, C Schürmann… - Journal of General …, 2021 - microbiologyresearch.org
… In contrast to the other coronaviruses tested, MERS-CoV does not use ACE2 as a receptor
… EGCG treatment inhibited the ACE2 receptor using coronavirus-pseudotyped vectors with IC…

Therapeutic potential of EGCG, a green tea polyphenol, for treatment of coronavirus diseases

J Park, R Park, M Jang, YI Park - Life, 2021 - mdpi.com
… 2 (NRF2) is known to reduce the expression of ACE2, a receptor for SARS-CoV-2 infection
in lung … entry into the host cell by modulating the viral spike protein and ACE2 interaction. …

… severe acute respiratory coronavirus disease 2 (SARS-CoV-2) infection by blocking the interaction of SARS-CoV-2 spike protein receptor-binding domain to human …

T Ohishi, T Hishiki, MS Baig, S Rajpoot, U Saqib… - PLoS …, 2022 - journals.plos.org
… -2 in vitro using the ACE2 receptor for entry; nevertheless, the … in green tea [49]; a cup of
green tea brewed from 2.5 g of tea … a broad of beneficial activities of green tea on human health, …

Green tea and Spirulina extracts inhibit SARS, MERS, and SARS-2 spike pseudotyped virus entry in vitro

J Joseph, A Ajay, VRA Das, VS Raj - BioRxiv, 2020 - biorxiv.org
… , we cloned the complete ACE2 or MERS-CoV receptor dipeptidyl peptidase 4 (DPP4) and
… The surface expression of ACE2 and DPP4 was confirmed by immunostaining using ACE2

EGCG, a green tea catechin, as a potential therapeutic agent for symptomatic and asymptomatic SARS-CoV-2 infection

M Chourasia, PR Koppula, A Battu, MM Ouseph… - Molecules, 2021 - mdpi.com
… spike protein with angiotensin I converting enzyme 2 (ACE2) receptors. Nevertheless, various
other clinical trials with anti-IL-6 receptor antibodies [32] concluded that mortality is subject …

Investigating the interaction between dietary polyphenols, the SARS CoV-2 spike protein and the ACE-2 receptor

D Schmidt, IH Said, N Ohl, M Sharifii, P Cotrell… - Food & Function, 2022 - pubs.rsc.org
… For both green tea infusions and EGCG the K D value could … ACE-2 receptor and SARS
CoV-2 S-protein binding domain. In a functional assay, 5-CQA, epicatechin, coffee and black tea