… Activator Protein-1 (AP-1) was one of the first mammalian TFs to be identified [1]. Since
then… At the cellular level, AP-1 TFs regulate cell proliferation by activating or inhibiting the …

… AP-1 and NF-κB, inducible by tumor promoters or oxidative stimuli, show … protein levels or
activation in response to tumor promoters in JB6 cells. We further demonstrated that AP-1 and …

… AP-1 is a sequence-specific transcriptional activator composed of members of the Jun and
… of mitogen-activated protein kinases (MAPKs) in regulation of AP-1 activity. The regulation …

… The activator protein-1 (AP-1) transcription factor is believed to be important in tumorigenesis
and altered AP-1 … We aimed to assess the potential role of AP-1 family members as novel …

… activator protein-1 (AP-1) as important in traversing tumor promotion and/or progression stages.
AP-1 … and Jun D) and Fos (cFos, Fos B, Fra 1, and Fra 2) or homodimers of Jun/Jun (10). …

… Activator protein 1 (aka activating protein 1, AP-1) is a critical … AP-1 has emerged as an
actively pursued drug discovery … in recent years (Figure 1). Accumulating evidence suggests that …

… Activator protein-1 (AP-1) is a transcription factor that consists of a … AP-1 involves a number
of processes such as proliferation, migration, and invasion in cells. Dysfunctional AP-1 activity …

… We describe a dominant negative (DN) to activation protein-1 (AP1) that inhibits DNA
binding in an equimolar competition. AP1 is a heterodimer of the oncogenes Fos and Jun, …

… The activator protein-1 (AP-1) is a dimeric transcription factor composed of proteins belonging
… JunD), Fos (c-Fos, FosB, Fra1 and Fra2) and activating transcription factor protein families. …

… inflammatory transcription factor AP-1 (activator protein-1) as a critical correlate in the initiation
and progression of vascular dysfunction, and atherogenesis. Hence, AP-1 inhibition has …