[HTML][HTML] Friend or foe? The roles of antioxidants in acute lung injury

Y Liu, S Zhou, D Xiang, L Ju, D Shen, X Wang, Y Wang - Antioxidants, 2021 - mdpi.com
Acute lung injury (ALI) is an acute hypoxic respiratory insufficiency caused by various intra-
and extra-pulmonary injury … (ROS) produced in the lungs plays an important role in the …

Oxidant-antioxidant balance in acute lung injury

JD Lang, PJ McArdle, PJ O'Reilly, S Matalon - Chest, 2002 - Elsevier
… of antioxidant defenses or that are lacking in antioxidant defenses can result in severe pulmonary
inflammation leading to acute lung injury … 8 Additionally, NO plays a multifaceted role in …

[HTML][HTML] Oxidative stress and inflammation in acute and chronic lung injuries

FS Bezerra, M Lanzetti, RT Nesi, AC Nagato, CP Silva… - Antioxidants, 2023 - mdpi.com
… the protective role of glutathione peroxidase 1 (GPx1) against acute lung inflammation …
of VILI, the antioxidant NAC was capable of reducing acute lung injury caused by MV [391]. …

[HTML][HTML] Oxidative stress and acute lung injury

CW Chow, MT Herrera Abreu, T Suzuki… - … journal of respiratory …, 2003 - atsjournals.org
… evidence supporting the role of oxidants and oxidative injury in the … oxidative lung injury is
to restore the oxidant/antioxidant balance by augmenting the intracellular pool of antioxidants. …

Role of oxidant stress in the adult respiratory distress syndrome: evaluation of a novel antioxidant strategy in a porcine model of endotoxin-induced acute lung injury

PK Gonzalez, J Zhuang, SR Doctrow, B Malfroy… - Shock, 1996 - journals.lww.com
… protection against acute lung injury induced in … acute lung injury, including arterial
hypoxemia, pulmonary hypertension, decreased dynamic pulmonary compliance, and pulmonary

Reactive oxygen species in acute lung injury

F Chabot, JA Mitchell, JM Gutteridge… - European Respiratory …, 1998 - Eur Respiratory Soc
… bined with decreased antioxidant capacity of pulmonary vascular tissue may … cells activated
by acute pulmonary rejection caused greater … Thus, antioxidants may have a beneficial role

[HTML][HTML] Antioxidant supplementation for the treatment of acute lung injury: A meta-analysis

AM Galvão, AD Andrade, MBS Maia… - Revista Brasileira de …, 2011 - SciELO Brasil
… (4) Disrupted oxidant antioxidant balance has a major role in the genesis of inflammatory …
as acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). (5,6) Antioxidants

Role of the pulmonary epithelium and inflammatory signals in acute lung injury

AM Manicone - Expert review of clinical immunology, 2009 - Taylor & Francis
Acute lung injury (ALI) is a clinical disease marked by respiratory failure due to disruption of
… The use of other disease-modifying therapy, including antioxidants to decompose ROS and …

Antioxidant strategies in respiratory medicine

M Christofidou-Solomidou, VR Muzykantov - Treatments in respiratory …, 2006 - Springer
Pulmonary oxidant stress plays an important pathogenetic role in disease conditions
including acute lung injury/adult respiratory distress syndrome (ALI/ARDS), hyperoxia, ischemia-…

[HTML][HTML] Dietary antioxidants significantly attenuate hyperoxia-induced acute inflammatory lung injury by enhancing macrophage function via reducing the …

V Patel, K Dial, J Wu, AG Gauthier, W Wu, M Lin… - International journal of …, 2020 - mdpi.com
acute lung injury and acute respiratory distress syndrome (ARDS). However, prolonged
exposure to hyperoxia can induce oxidative inflammatory lung injury. … -induced acute lung injury (…