Integrated bioinformatic analysis of SARS-CoV-2 infection related genes ACE2, BSG and TMPRSS2 in aerodigestive cancers

C He, X Hua, S Sun, S Li, J Wang… - Journal of Inflammation …, 2021 - Taylor & Francis
… that patients with aerodigestive cancers could be more susceptible to SARS-CoV-2; these
findings were consistent with other clinical observations that lung cancer and CRC were the …

[HTML][HTML] Lung cancer models reveal SARS-CoV-2-induced EMT contributes to COVID-19 pathophysiology

CA Stewart, CM Gay, K Ramkumar, KR Cargill… - BioRxiv, 2021 - ncbi.nlm.nih.gov
… from the aerodigestive and … aerodigestive and lung cancer cell lines have a broad range
of ACE2 and TMRPSS2 expression and would serve as good models for studying SARS-CoV

The influence of the SARS-CoV-2 pandemic on esophagogastric cancer services: an international survey of esophagogastric surgeons

SK Kamarajah, SR Markar, P Singh… - Diseases of the …, 2020 - academic.oup.com
… to patients by their center prior to the SARS CoV-2 pandemic whereas in round 1 and
round 2 focusses on oncological therapy used during the SARS CoV-2 pandemic. P-values in …

Lung cancer models reveal severe acute respiratory syndrome coronavirus 2–induced epithelial-to-mesenchymal transition contributes to coronavirus disease 2019 …

CA Stewart, CM Gay, K Ramkumar, KR Cargill… - Journal of Thoracic …, 2021 - Elsevier
… Our bulk data suggest that aerodigestive and lung cancer cell lines have a broad range of …
for studying SARS-CoV-2 infection, consistent with the observation that SARS-CoV-2 virus has …

1735P SARS-CoV-2 infection induces EMT-like molecular changes, including ZEB1-mediated repression of the viral receptor ACE2, in lung cancer models

CA Stewart, C Gay, K Ramkumar… - Annals of …, 2020 - annalsofoncology.org
… Our bulk data suggests that aerodigestive and lung cancer … serve as good models for studying
SARS-CoV-2 infection. We assessed … Furthermore, SARS-CoV-2 infection reduces ACE2 …

SARS-CoV-2 infection and cardioncology: from cardiometabolic risk factors to outcomes in cancer patients

V Quagliariello, A Bonelli, A Caronna, G Conforti… - Cancers, 2020 - mdpi.com
… , male cancer patients have an increased risk of SARS-CoV-2 … of SARS-CoV-2 infection;
prostate or breast cancer patients … incidence and mortality in breast, lung, upper aerodigestive

Digestive symptoms of COVID-19 and expression of ACE2 in digestive tract organs

J Xu, M Chu, F Zhong, X Tan, G Tang, J Mai, N Lai… - Cell death …, 2020 - nature.com
… , to early cancer. Our data might provide a theoretical basis for screening the SARS-CoV-2 …
ACE2-positive cell proportion in aerodigestive cancers. *ACE2-positive cell proportion in …

SARS-CoV-2 tropism across the upper aerodigestive tract

S Torretta, L Pignataro, P Marchisio… - International Journal …, 2021 - journals.sagepub.com
… to achieving a comprehensive knowledge of SARS-CoV-2 pathogenesis and transmission
… to SARS-CoV-2 infection across specific anatomic subsites of the upper aerodigestive tract, …

Comprehensive and integrative analysis of two novel SARS-CoV-2 entry associated proteases CTSB and CTSL in healthy individuals and cancer patients

Y Huang, S Li, S Huang, J Tu, X Chen… - … in Bioengineering and …, 2022 - frontiersin.org
… in pan-cancer. Finally… cancer patients may be more susceptible to SARS-CoV-2 infection.
Our data suggested that CTSB/L are overexpressed in aerodigestive and genitourinary cancers

Increased susceptibility of SARS-CoV2 infection on oral cancer patients; cause and effects: An hypothesis

A Chauhan, S Ghoshal, A Pal - Medical Hypotheses, 2020 - Elsevier
… This virus is transmitted directly or indirectly through the upper aerodigestive tract. As it is
evident from the recent studies that SARS-CoV-2 requires host enzyme Furin to activate …