Early airway infection, inflammation, and lung function in cystic fibrosis

GM Nixon, DS Armstrong, R Carzino… - Archives of disease in …, 2002 - adc.bmj.com
function and airway inflammation. Unfortunately, the relation between respiratory symptoms
and lung function … and pulmonary function in infants and young children with cystic fibrosis. …

Airway inflammation in cystic fibrosis

A Elizur, CL Cannon, TW Ferkol - Chest, 2008 - Elsevier
… with cystic fibrosis (CF) experience declining pulmonary function related to chronic airway
mediators that promote neutrophil influx into the airways. This inflammatory response may be …

The evolution of airway function in early childhood following clinical diagnosis of cystic fibrosis

SC Ranganathan, J Stocks, C Dezateux… - American journal of …, 2004 - atsjournals.org
… investigate the evolution of airway function in infants newly diagnosed with cystic fibrosis (CF)…
Airway function is diminished soon after diagnosis in infants with CF and does not catch up …

Airway function in infants newly diagnosed with cystic fibrosis

SC Ranganathan, C Dezateux, A Bush, SB Carr… - The Lancet, 2001 - thelancet.com
… We measured the airway function of newly diagnosed infants … We compared the airway
function of 33 infants with cystic fibrosisAirway function was significantly reduced in children with …

A functional anatomic defect of the cystic fibrosis airway

SE Birket, KK Chu, L Liu, GH Houser… - American journal of …, 2014 - atsjournals.org
… By analyzing colocalized, synchronous measures of the airway functional anatomy, our
findings further indicate that the MCT apparatus of the CF airway, and the impact of PCL …

Airway epithelium dysfunction in cystic fibrosis and COPD

V De Rose, K Molloy, S Gohy, C Pilette… - Mediators of …, 2018 - Wiley Online Library
… The airway epithelium plays a crucial role in maintaining normal airway functions. Major
molecular and morphologic changes occur in the airway epithelium in both CF and COPD, and …

Airway remodelling and its relationship to inflammation in cystic fibrosis

N Regamey, PK Jeffery, EWFW Alton, A Bush… - Thorax, 2011 - thorax.bmj.com
… (A) Traditional view of the sequence of events leading to airway remodelling in cystic fibrosis
… evolution of airway function in early childhood following clinical diagnosis of cystic fibrosis. …

Airway remodelling in children with cystic fibrosis

TN Hilliard, N Regamey, JK Shute, AG Nicholson… - Thorax, 2007 - thorax.bmj.com
airway function. But if remodelling is a separate process, relating to some aspect of cystic
fibrosis … dysfunction, new therapeutic approaches to preserve airway function may be required. …

Airway inflammation in cystic fibrosis: molecular mechanisms and clinical implications

M Cohen-Cymberknoh, E Kerem, T Ferkol, A Elizur - Thorax, 2013 - thorax.bmj.com
Airway epithelial cells and immune cells participate in the … found in the lung of patients with
cystic fibrosis (CF). Intense … lower airway epithelium of people with advanced cystic fibrosis

The cystic fibrosis airway microbiome

SV Lynch, KD Bruce - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
… Whether this is a function of our inability to obtain clean lower airway samples in this
population is a possibility. However, it is also conceivable, particularly in light of recent studies …