… analyses have greatly increased our understanding of the genetic etiology of AD. However,
… alcohol dependence genetics in the GWAS and post-GWAS eras. AD, alcohol dependence; …

… of formal genetic studies, summarizes the results of earlier molecular–genetic investigations,
and presents a detailed overview of all published GWAS in the field of alcohol dependence …

… ’ or ‘alcohol addiction’. … genetic influences on alcohol dependence. Finally, we searched
for PubMed-indexed articles describing GWAS of alcohol dependence by using the term ‘GWAS…

… In this study, our approach to identifying genetic risk factors for alcohol dependence
focused on the use of the AUDIT, a brief self-report measure that allows for large-scale data …

… identify genes related to the vulnerability for alcohol dependence: … studies and genome-wide
association studies (GWAS); and … Several GWAS that focused on alcohol dependence were …

… Excessive alcohol use is a leading contributor to morbidity and mortality. One in 20 deaths
worldwide is attributable to alcohol consumption, as is 5.1% of the global burden of disease 1 …

… Identification of genes that contribute to alcohol dependence … or GWAS approach in humans
and have proved to be very … a GWAS and a follow-up study for alcohol dependence using …

… We propose a shift from cataloging statistical genetic associations to using post-GWAS
tools to make biological sense of them. Incorporating the strategies outlined here should help …

… For alcohol phenotypes, investigations of GWAS-identified variants have begun to disentangle
which genes directly impact alcohol use (eg, alcohol metabolism genes) and which have …

… -wide significant and/or replicable risk genes for alcohol dependence with potential
biological functions, which is highly necessary for the follow-up studies in the post-GWAS era. …