Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects

JB Toledo, H Zetterberg, AC Van Harten, L Glodzik… - Brain, 2015 - academic.oup.com
… genotype strongly affects the levels of cerebrospinal fluid amyloid-β 1-42 … Alzheimer's disease
CSF biomarkers in 1233 cognitively normal subjects aged 40–85 years. Alzheimer disease

Metabolite profiling of Alzheimer's disease cerebrospinal fluid

C Czech, P Berndt, K Busch, O Schmitz, J Wiemer… - PloS one, 2012 - journals.plos.org
… criteria in order to characterize the disease at a pre-dementia stage. It was proposed to
take into account neuroimaging biomarkers and cerebrospinal fluid (CSF) analysis of amyloid …

Cerebrospinal fluid biomarkers for Alzheimer's disease

K Blennow, H Zetterberg - Journal of Alzheimer's Disease, 2009 - content.iospress.com
… of Alzheimer's disease (AD), which has been translated into an ongoing development of
disease-… Molecular aberrations in the AD brain are reflected in the cerebrospinal fluid (CSF). The …

Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

K Blennow, H Hampel, M Weiner… - Nature Reviews …, 2010 - nature.com
… -modifying drugs have created a need for biomarkers that reflect core elements of the
disease process. Here, we review the development of candidate cerebrospinal fluid (CSF) and …

Cerebrospinal fluid biomarkers of Alzheimer's disease

AM Fagan, DM Holtzman - Biomarkers in medicine, 2010 - Taylor & Francis
… in disease diagnosis and prognosis, and assess disease risk … have demonstrated that
Alzheimer's disease pathology can … the most promising cerebrospinal fluid biomarkers, highlights …

Clinical utility of cerebrospinal fluid biomarkers in the diagnosis of early Alzheimer's disease

K Blennow, B Dubois, AM Fagan, P Lewczuk… - Alzheimer's & …, 2015 - Elsevier
… Although protein content is lower in cerebrospinal fluid (CSF) than in serum, CSF is an ideal
source for developing viable biomarkers in AD as it directly interacts with the extracellular …

Detection of proteins in normal and Alzheimer's disease cerebrospinal fluid with a sensitive sandwich enzyme‐linked immunosorbent assay

M Vandermeeren, M Mercken… - Journal of …, 1993 - Wiley Online Library
… in Alzheimer's disease as … Alzheimer's disease. Also, CSF levels in a large group of
patients with a diversity of neurological diseases showed overlap with CSF levels in Alzheimer's

Cerebrospinal fluid markers for prediction of Alzheimer's disease

H Zetterberg, LO Wahlund, K Blennow - Neuroscience letters, 2003 - Elsevier
… between mild cognitive impairment (MCI) and incipient Alzheimer's disease (AD). We
show that a combination of three cerebrospinal fluid biochemical markers, total-tau, phospho-tau …

Race modifies the relationship between cognition and Alzheimer's disease cerebrospinal fluid biomarkers

JC Howell, KD Watts, MW Parker, J Wu… - Alzheimer's research & …, 2017 - Springer
… We hypothesized that etiologic biomarkers for AD such as cerebrospinal fluid (CSF) protein
profiles can improve the antemortem characterization of AD and non-AD pathology in older …

Cerebrospinal fluid biomarkers for early and differential Alzheimer's disease diagnosis

M Bjerke, S Engelborghs - Journal of Alzheimer's Disease, 2018 - content.iospress.com
… An accurate and early diagnosis of Alzheimer’s disease (AD) is important to select optimal …
been made in the development and validation of cerebrospinal fluid (CSF) biomarkers for the …