C Czech, P Berndt, K Busch, O Schmitz, J Wiemer… - PloS one, 2012 - journals.plos.org
… criteria in order to characterize the disease at a pre-dementia stage. It was proposed to take into account neuroimaging biomarkers and cerebrospinalfluid (CSF) analysis of amyloid …
K Blennow, H Zetterberg - Journal of Alzheimer's Disease, 2009 - content.iospress.com
… of Alzheimer'sdisease (AD), which has been translated into an ongoing development of disease-… Molecular aberrations in the AD brain are reflected in the cerebrospinalfluid (CSF). The …
K Blennow, H Hampel, M Weiner… - Nature Reviews …, 2010 - nature.com
… -modifying drugs have created a need for biomarkers that reflect core elements of the disease process. Here, we review the development of candidate cerebrospinalfluid (CSF) and …
AM Fagan, DM Holtzman - Biomarkers in medicine, 2010 - Taylor & Francis
… in disease diagnosis and prognosis, and assess disease risk … have demonstrated that Alzheimer'sdisease pathology can … the most promising cerebrospinalfluid biomarkers, highlights …
K Blennow, B Dubois, AM Fagan, P Lewczuk… - Alzheimer's & …, 2015 - Elsevier
… Although protein content is lower in cerebrospinalfluid (CSF) than in serum, CSF is an ideal source for developing viable biomarkers in AD as it directly interacts with the extracellular …
M Vandermeeren, M Mercken… - Journal of …, 1993 - Wiley Online Library
… in Alzheimer'sdisease as … Alzheimer'sdisease. Also, CSF levels in a large group of patients with a diversity of neurological diseases showed overlap with CSF levels in Alzheimer's …
H Zetterberg, LO Wahlund, K Blennow - Neuroscience letters, 2003 - Elsevier
… between mild cognitive impairment (MCI) and incipient Alzheimer'sdisease (AD). We show that a combination of three cerebrospinalfluid biochemical markers, total-tau, phospho-tau …
… We hypothesized that etiologic biomarkers for AD such as cerebrospinalfluid (CSF) protein profiles can improve the antemortem characterization of AD and non-AD pathology in older …
M Bjerke, S Engelborghs - Journal of Alzheimer's Disease, 2018 - content.iospress.com
… An accurate and early diagnosis of Alzheimer’s disease (AD) is important to select optimal … been made in the development and validation of cerebrospinalfluid (CSF) biomarkers for the …