Alterations of Alzheimer's disease in the cholesterol‐fed rabbit, including vascular inflammation: preliminary observations

DL Sparks, YUMIN KUO, A Roher… - Annals of the New …, 2000 - Wiley Online Library
… the cholesterol-fed rabbits (BD) compared to control (A), and extracellular deposits plaque-like
were observed in two of six cholesterol… cortex from each control and cholesterol-fed rabbit. …

Elevated plasma triglyceride levels precede amyloid deposition in Alzheimer's disease mouse models with abundant Aβ in plasma

BL Burgess, SA McIsaac, KE Naus, JY Chan… - … of disease, 2006 - Elsevier
… TG levels, plasma and brain Aβ levels, and extent of amyloid deposition over time. Here we
report that plasma cholesterol levels are not significantly altered in any of the murine models …

Cholesterol in neurologic disorders of the elderly: stroke and Alzheimer's disease

AB Reiss, KA Siller, MM Rahman, ESL Chan… - Neurobiology of …, 2004 - Elsevier
… Tangier disease is a rare genetic disorder characterized by … ester deposition in tissues,
cholesterol ester accumulation in macrophages and a high prevalence of cardiovascular disease. …

CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer's disease

F Djelti, J Braudeau, E Hudry, M Dhenain, J Varin… - Brain, 2015 - academic.oup.com
… with other mechanisms that induce amyloid deposits and the formation of neurofibrillary
tangles and … On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal …

Cholesterol and Alzheimer's disease risk: a meta-meta-analysis

O Sáiz-Vazquez, A Puente-Martínez, S Ubillos-Landa… - Brain sciences, 2020 - mdpi.com
… that cholesterolcholesterol on the development AD. Then, we assessed the effect of serum
levels of low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (…

Coronary artery disease, hypertension, ApoE, and cholesterol: a link to Alzheimer's disease?

DL Sparks - Annals of the New York Academy of Sciences, 1997 - Wiley Online Library
cholesterol-fed rabbit included increasingly severe neuronal accumulation of β-amyloid
immunoreactivity with later extracellular deposition … and blood of the cholesterol-fed rabbits. The …

Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer's disease

V Roca-Agujetas, E Barbero-Camps, C de Dios… - Molecular …, 2021 - Springer
… been shown to significantly reduce Aβ depositions and prevent the cognitive impairment in
AD … Both mutations are associated with early-onset Alzheimer disease. In turn, SREBF2 mice …

Endolysosome mechanisms associated with Alzheimer's disease-like pathology in rabbits ingesting cholesterol-enriched diet

X Chen, JF Wagener, DH Morgan, L Hui… - … of Alzheimer's …, 2010 - content.iospress.com
… Endolysosome involvement in cholesterol-induced intraneuronal depositions of … the extent
to which the cholesterol-enriched diet affected intraneuronal deposition of phosphorylated tau …

[PDF][PDF] Amyloid beta, neural lipids, cholesterol & Alzheimer's disease

NV Koudinova, A Kontush, TT Berezov, AR Koudinov - pathology, 2003 - Citeseer
ALZHEIMER’S DISEASE In a separate set of experiments by modifying rat cholesterol status
with the diet containing 2 % cholesterol … to amyloid deposition of Alzheimer's disease brain …

Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease

RG Cutler, J Kelly, K Storie… - Proceedings of the …, 2004 - National Acad Sciences
… Because levels of ceramides and cholesterol were increased … the hypothesis that Aβ
deposition was responsible for these … C24:0, cholesterol and cholesterol esters were significantly …