… In this review, we focus on the earlydetection of AD, particularly in the context of subjects with memory complaints who do not yet match criteria for AD but who are at high risk of …
SE Counts, MD Ikonomovic, N Mercado, IE Vega… - …, 2017 - Elsevier
… of potential disease-modifying drugs for Alzheimer'sdisease (… Thus, well-validated biomarkers for the earlydetection and … identify people in the earliest stages of the disease when drug …
L Mosconi, M Brys, L Glodzik-Sobanska… - Experimental …, 2007 - Elsevier
… In summary, the use of structural and functional neuroimaging for the earlydetection of the effects of AD on the brain has been successful even in the earlier stages of disease when …
… In this study, an end-to-end Alzheimer’s diseaseearlydetection and classification (E 2 AD 2 C) framework is established focused on deep learning approaches and convolutional neural …
S Teipel, A Drzezga, MJ Grothe, H Barthel… - The Lancet …, 2015 - thelancet.com
… brain changes related to Alzheimer'sdisease in the research setting are PET-based amyloid markers, which detect molecular pathology specific to Alzheimer'sdisease, and markers of …
B Dubois, G Picard, M Sarazin - Dialogues in clinical neuroscience, 2009 - Taylor & Francis
… The answer is yes, because Alzheimer'sdisease is already symptomatic long before dementia. This raises the issue of the definition of Alzheimer'sdisease: what is Alzheimer'sdisease…
… clinical decision support that predicts the Alzheimer’s disease (AD) stage using multi… disease burden of AD is projected to reach $2 trillion by 2030 15 , which necessitates earlydetection…
AD Cohen, WE Klunk - Neurobiology of disease, 2014 - Elsevier
… detection of early and preclinical Alzheimer'sdisease (AD) has become of central importance following publication of the NIA-Alzheimer's … (FDG) is able to detectearly AD pathological …
R Mistur, L Mosconi, S De Santi… - Journal of clinical …, 2009 - synapse.koreamed.org
… different PET tracers and CSF markers of pathology to improve the earlydetection of AD. … Overall, the addition of other PET tracers to FDG-PET may be of use in the earlydetection of AD…