… on the genomics landscape of AD and then discuss the ongoing efforts in integrating GWAS findings in LOAD with functionalgenomics in order to identify putative functional genes and …
X Wang, ML Michaelis, EK Michaelis - Current genomics, 2010 - ingentaconnect.com
… the functional status of cells is determined to a large extent by their genomic activity, genomic … Secondly, we collect and carry out an analysis of the published functionalgenomic studies …
R Cacabelos, L Fernández-Novoa, L Corzo… - Neurological …, 2004 - Taylor & Francis
… differentiate the phenotypic profiles and functionalgenomics of AD and dementia with vascular component (DVC) in order to identify biological and genomic differences between the two …
Y Li, M Xu, BL Xiang, X Li, DF Zhang, H Zhao… - …, 2023 - nature.com
… In summary, we performed a functionalgenomics assay and identified causal variant underlying the protective CTSH locus for AD. Further studies with this gene are definitely needed to …
Alzheimer'sdisease (AD) and frontotemporal lobar degeneration (FTLD) are complex human brain disorders that affect an increasing number of people worldwide. With the …
R Cacabelos, L Fernández-Novoa… - Methods and findings …, 2005 - europepmc.org
… approach to Alzheimer'sdiseasefunctionalgenomics is to … of functionalgenomics to Alzheimer'sdisease can be a … mechanisms associated with Alzheimer'sdisease-related …
HD Li, CC Funk, K McFarland… - Alzheimer's & …, 2021 - Wiley Online Library
… disease (AD) remains unexplored. We performed genome-wide analysis of IR through … from the Accelerating Medicines Partnership-Alzheimer'sDisease project. We identified 4535 and …
R Cacabelos, V Lombardi… - … Alzheimer Disease …, 2004 - books.google.com
… Functionalgenomics strategies can help to improve our understanding of the interactions between genomic and environmental factors in the activation of pathogenic mechanisms …
V Wiwanitkit - Annals of Indian Academy of Neurology, 2013 - journals.lww.com
… [ 7 8 ] In this work, the assigned primary template was the human genome. The input ontology term is “Alzheimer'sdisease.” Gene in range v 2.02 with length 1 Mbp was focused in the …