The application of functional genomics to Alzheimer's disease

R Cacabelos - Pharmacogenomics, 2003 - Future Medicine
… expression of the disease under the … as genomic clusters integrating the different genotype
combinations of AD-related genes is a suitable strategy to investigate functional genomics in …

[HTML][HTML] Genomics and functional genomics of Alzheimer's disease

MI Kamboh - Neurotherapeutics, 2023 - Elsevier
… on the genomics landscape of AD and then discuss the ongoing efforts in integrating GWAS
findings in LOAD with functional genomics in order to identify putative functional genes and …

Functional genomics of brain aging and Alzheimer's disease: focus on selective neuronal vulnerability

X Wang, ML Michaelis, EK Michaelis - Current genomics, 2010 - ingentaconnect.com
… the functional status of cells is determined to a large extent by their genomic activity, genomic
… Secondly, we collect and carry out an analysis of the published functional genomic studies …

Phenotypic profiles and functional genomics in Alzheimer's disease and in dementia with a vascular component

R Cacabelos, L Fernández-Novoa, L Corzo… - Neurological …, 2004 - Taylor & Francis
… differentiate the phenotypic profiles and functional genomics of AD and dementia with vascular
component (DVC) in order to identify biological and genomic differences between the two …

Functional genomics identify causal variant underlying the protective CTSH locus for Alzheimer's disease

Y Li, M Xu, BL Xiang, X Li, DF Zhang, H Zhao… - …, 2023 - nature.com
… In summary, we performed a functional genomics assay and identified causal variant underlying
the protective CTSH locus for AD. Further studies with this gene are definitely needed to …

[HTML][HTML] Alzheimer's disease models and functional genomics—How many needles are there in the haystack?

J Götz, M Matamales, NN Goetz, LM Ittner… - Frontiers in …, 2012 - frontiersin.org
Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD) are complex
human brain disorders that affect an increasing number of people worldwide. With the …

Molecular genetics of Alzheimer's disease and aging.

R Cacabelos, L Fernández-Novoa… - Methods and findings …, 2005 - europepmc.org
… approach to Alzheimer's disease functional genomics is to … of functional genomics to
Alzheimer's disease can be a … mechanisms associated with Alzheimer's disease-related …

Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease

HD Li, CC Funk, K McFarland… - Alzheimer's & …, 2021 - Wiley Online Library
disease (AD) remains unexplored. We performed genome-wide analysis of IR through … from
the Accelerating Medicines Partnership-Alzheimer's Disease project. We identified 4535 and …

A functional genomics approach to the analysis of biological markers in Alzheimer disease

R Cacabelos, V Lombardi… - … Alzheimer Disease …, 2004 - books.google.com
Functional genomics strategies can help to improve our understanding of the interactions
between genomic and environmental factors in the activation of pathogenic mechanisms …

[HTML][HTML] Physiological genomics analysis for Alzheimer's disease

V Wiwanitkit - Annals of Indian Academy of Neurology, 2013 - journals.lww.com
… [ 7 8 ] In this work, the assigned primary template was the human genome. The input ontology
term is “Alzheimer's disease.” Gene in range v 2.02 with length 1 Mbp was focused in the …