[HTML][HTML] Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: Recent advances

W Wang, F Zhao, X Ma, G Perry, X Zhu - Molecular neurodegeneration, 2020 - Springer
… novel promising therapeutic targets for the disease. In this review, … of mitochondria dysfunction
in the pathogenesis of AD and discuss mechanisms underlying mitochondrial dysfunction

[HTML][HTML] Oxidative stress and mitochondrial dysfunction in Alzheimer's disease

X Wang, W Wang, L Li, G Perry, H Lee, X Zhu - … -Molecular Basis of Disease, 2014 - Elsevier
Mitochondrial dysfunction is likely involved in the initiation and/or amplification of oxidative
… of Alzheimer disease. Oxidative stress can negatively impact mitochondrial integrity and …

[HTML][HTML] Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

PI Moreira, C Carvalho, X Zhu, MA Smith… - … Basis of Disease, 2010 - Elsevier
Alzheimer's disease. This review discusses evidence indicating that mitochondrial dysfunction
has an early and preponderant role in Alzheimer's disease. Furthermore, the link between …

The role of mitochondrial dysfunction in Alzheimer's disease pathogenesis

T Ashleigh, RH Swerdlow, MF Beal - Alzheimer's & Dementia, 2023 - Wiley Online Library
… of Alzheimer's disease (AD), we examine the central role of mitochondrial dysfunction in AD.
… and biochemical abnormalities including mitochondrial dysfunction. Conventional thinking …

Mitochondrial dysfunction and Alzheimer's disease

A Maruszak, C Żekanowski - Progress in Neuro-Psychopharmacology and …, 2011 - Elsevier
… hypotheses for Alzheimer's disease (AD) etiology implicates mitochondrial dysfunction
and oxidative … In this review we focus on the role of mitochondria and mitochondrial DNA (mtDNA) …

Mechanisms of mitochondrial dysfunction in Alzheimer's disease

C Cadonic, MG Sabbir, BC Albensi - Molecular neurobiology, 2016 - Springer
mitochondrial dysfunctions found in Alzheimer’s disease. Explicitly shown is altered
morphology of the mitochondria and synaptic space, as well as the reduced level of mitochondrial

Alzheimer's disease: a lesson from mitochondrial dysfunction

PI Moreira, MS Santos, CR Oliveira - Antioxidants & redox signaling, 2007 - liebertpub.com
… mitochondrial dysfunction is intimately associated with Alzheimer’s disease pathogenesis. …
between mitochondrial dysfunction/oxidative stress and autophagy in Alzheimer’s disease is …

Mitochondrial dysfunction: different routes to Alzheimer's disease therapy

P Picone, D Nuzzo, L Caruana… - Oxidative medicine …, 2014 - Wiley Online Library
… Moreover, we analyze how these vulnerable points for Aβ-mediated mitochondrial dysfunction
may be distinctive and perhaps complementary therapeutic intervention targets for AD. …

[HTML][HTML] Mitochondrial dysfunction and oxidative stress in Alzheimer's disease

A Misrani, S Tabassum, L Yang - Frontiers in aging neuroscience, 2021 - frontiersin.org
… Here, we review studies that suggest a role of mitochondrial dysfunction and the consequent
ROS production in AD pathology and provide a context to explain current and future …

Mitochondrial dysfunction in aging and Alzheimer's disease: strategies to protect neurons

PH Reddy - Antioxidants & redox signaling, 2007 - liebertpub.com
mitochondria have revealed that abnormalities in mitochondria may lead to mitochondrial
dysfunction … and those with neurodegenerative diseases, including Alzheimer’s disease (AD). …