… therapies with early disease modification. A better understanding of the natural history of the
preclinical … factors (ie, triggers) of disease progression, and related ethical issues is needed. …

… , and address factors that may influence disease course. Understanding the natural history
of AD will allow better targeting of the disease-modifying treatments that are on the horizon. …

The study aim was to describe the temporal course of cognitive decline in Alzheimer's disease
(AD). We selected 226 persons from 2 longitudinal clinical-pathological studies who were …

… The primary objective of this study was to define the natural history of Alzheimer's Disease
… for this study if the diagnosis of Alzheimer's Disease was confirmed by autopsy and if the …

… It is not the purpose of this paper to try and establish the natural history and differential
diagnosis of PD but the evidence we have collected would suggest that this too can probably be …

… Part XIV: demographic and clinical predictors of survival in patients with Alzheimer disease.
Neurology 46: 656–660 Heyman A, Peterson B, Cillenbaum G, Pieper C. (1997) Predictors …

… However, the accumulation of data on the natural history of sporadic AD, that … natural
history of tau pathology in the aging human brain that develops or not Alzheimer’s disease…

… Despite the fact that dementia, especially Alzheimer's disease … made, the natural history of
the disease still remains poorly … Since the concept of the natural history of a disease is very …

… Patients with early-onset disease, patients with more years of formal education, and male
patients tend to manifest psychiatric changes later in the natural history of the disease, relative …

… can alter the natural course of Alzheimer's disease. For example… effects of CEIs on the natural
history of the disease in a non-… on the traditional milestones of Alzheimer's disease (time to …