Vascular abnormalities: The insidious pathogenesis of Alzheimer's disease

J Shi, G Perry, MA Smith, RP Friedland - Neurobiology of Aging, 2000 - Elsevier
Vascular abnormalities diminish supplies of nutrients and … not be surprising that vascular
abnormalities are often linked to … critically address the role of vascular abnormalities in AD. Our …

[HTML][HTML] An integrated view on vascular dysfunction in Alzheimer's disease

J Klohs - Neurodegenerative Diseases, 2020 - karger.com
… b Histopathology shows vascular abnormalities such as tortuous arterioles and string
vessels (arrows) in the AD brain. Celloidin sections were stained for collagen [215]. c Scanning …

[HTML][HTML] Evidence of endothelial dysfunction in the development of Alzheimer's disease: is Alzheimer'sa vascular disorder?

RJ Kelleher, RL Soiza - American journal of cardiovascular disease, 2013 - ncbi.nlm.nih.gov
… This article summarises data regarding cardiovascular risk factors, vascular abnormalities
and brain endothelial damage in AD. In view of accumulating evidence of vascular pathology …

The blood‐brain barrier and cerebrovascular pathology in Alzheimer's disease

RN Kalaria - Annals of the New York Academy of Sciences, 1999 - Wiley Online Library
… in AD patients who exhibit peripheral vascular abnormalities such as hypertension,
cardiovascular disease and diabetes. Whether these vascular lesions along with perivascular …

Neuropathological diagnosis of vascular cognitive impairment and vascular dementia with implications for Alzheimer's disease

RN Kalaria - Acta neuropathologica, 2016 - Springer
… and the vascular abnormalities that may have … vascular disease and should be taken into
account when attributing causes to VaD. As discussed above, parenchymal abnormalities of …

Vascular basis of Alzheimer's pathogenesis

JC de la Torre - Annals of the New York Academy of sciences, 2002 - Wiley Online Library
Alzheimer's disease (AD) is primarily a vascular disorder. This conclusion is supported by
the following evidence: (1) epidemiologic studies linking vascular … show abnormal patterns of …

Pathological changes within the cerebral vasculature in Alzheimer's disease: New perspectives

RA Fisher, JS Miners, S Love - Brain Pathology, 2022 - Wiley Online Library
Alzheimer's Disease Neuroimaging Initiative (ADNI) and modelling of late-onset AD (LOAD)
suggest that vascular … cerebral vascular abnormalities in AD, and for testing novel therapies. …

Small vessel disease and Alzheimer's dementia: pathological considerations

RN Kalaria - Cerebrovascular Diseases, 2002 - karger.com
Alzheimer disease (AD) cases may exhibit significant cerebrovascular pathology, which
constitutes distinct small vessel disease (… and other vascular abnormalities typical of SVD in AD. […

Vascular factors in Alzheimer's disease

RN Kalaria - International Psychogeriatrics, 2003 - cambridge.org
… hemorrhages and other vascular abnormalities typical of small vessel disease in AD. In …
and biochemical methods have demonstrated abnormalities in various cellular el& ments of …

[PDF][PDF] Vascular signaling abnormalities in Alzheimer disease

J MARTINEZ - Cleveland Clinic journal of medicine, 2011 - academia.edu
Alzheimer disease (AD) express or release a myriad of factors that have been implicated in
vascular … In addition, we have documented that signaling cascades associated with vascular