… vasculardysfunction in living AD patients. However, none of these trials included vascular dysfunction … Might vasculardysfunction indeed be an intermediate pathophysiological process …
G Bomboi, L Castello, F Cosentino, F Giubilei… - Neurological …, 2010 - Springer
… For instance, identification of vasculardysfunction may constitute a powerful predictor … dysfunction at level of the neurovascular unit plays a role in the pathogenesis of Alzheimerdisease…
… vasculardysfunction in animal models, including amyloid-β-independent vascular changes, amyloid-β-dependent vascular … Last, we emphasize Alzheimerdiseasevasculardysfunction, …
… Vasculardysfunction has a critical role in Alzheimer’s disease (AD). Recent data from brain imaging studies in humans and animal models suggest that cerebrovascular dysfunction …
… in Alzheimer'sdisease results from unsuccessful vascular repair … Does vasculardysfunction cause neuronal dysfunction? In … vasculardysfunction is tightly linked to neuronal dysfunction. …
C Lange-Asschenfeldt, G Kojda - Experimental gerontology, 2008 - Elsevier
… regarding the primary prevention of AD from a vascular point of view. First, we will point out the mutual interconnection of vasculardysfunction and AD pathophysiology. We will then …
BV Zlokovic - Advanced drug delivery reviews, 2002 - Elsevier
… This review is focused on specific aspects of vasculardysfunction in AD related to … dysfunction for Aβ is probably a late event in AD possibly resulting form disease-specific vascular …
Y Yamazaki, T Kanekiyo - International journal of molecular sciences, 2017 - mdpi.com
… dysfunction of the BBB is likely involved in the pathogenesis of several neurological diseases, including Alzheimer’s disease (… Thus, current evidence suggests that BBB dysfunction may …
N Nicolakakis, E Hamel - Journal of Cerebral Blood Flow & …, 2011 - journals.sagepub.com
… These findings challenged the view that soluble Aβ could initiate vasculardysfunction at concentrations inhibiting neuronal function. It also suggested that vascular deficits may act as …