… vascular dysfunction and mitochondrial failure, both in neurons and glia and in brain vascular
… target for the development of Alzheimer's disease and Alzheimer disease-like pathology in …

… Increasing evidence points to non-structural vascular dysfunction rather than structural
abnormalities of vessel walls as the main cause of cerebral hypoperfusion in AD. Several …

… hypothesis for Alzheimer's disease. It is hypothesized that chronic mild exposure of different
(vascular) risk factors may play a role in the development of Alzheimers disease. These …

… of arteriolosclerosis, and Aβ-, tau- and endothelin-related vascular dysfunction. The relative
contributions of these processes vary considerably both between and within the diseases. …

… as well as vascular dysfunction associated with AD. … vascular dysfunction. This evidence
includes existence of cerebrovascular disease in the AD brain, blood brain barrier dysfunction, …

… vascular basis for neuronal atrophy in both the temporal and frontal lobes in VaD that is
entirely independent of any Alzheimer … resulting in executive dysfunction and other cognitive …

… vascular dementia and Alzheimer’s disease (AD).It remains unclear whether controlling
vascular risk factors, vascular … dysfunction in Alzheimer disease. Nat Med 2005; 11:959 –965. …

… vascular risk factors (VRF), neurovascular unit dysfunction (… continuum between AD and
vascular dementia. Shared … Moreover, vascular disease and several comorbidities may …

… mechanisms of brain dysfunction linked to vascular risk factors, … prevails in the ethiology of
Alzheimer's Disease (AD), it has … Cerebral vascular dysfunction during hypercholesterolemia. …

… of the vascular dysfunction observed in AD, … vascular aging/vascular dysfunction at its
earliest stages. Finally, we will discuss the reciprocal interplay of frailty, cardiovascular diseases (…