The pathology of Alzheimer disease (AD) damages structural and functional brain networks,
resulting in cognitive impairment. The results of recent connectomics studies have now …

… the biomarkers and Alzheimer’s disease genetic risk, age at onset and disease duration. …
genome-wide association study for association of disease risk genes with these biomarkers. …

… Three decades of genetic research in Alzheimer disease (AD) have substantially broadened
our understanding of the pathogenetic mechanisms leading to neurodegeneration and …

… The most successful diagnostic tests for AD are based on advances in molecular genetics, …
from an ideal biomarker for AD? It is probably unrealistic to expect that any biomarker be 100…

… and planning group for genetics within the Alzheimer's Disease Neuroimaging Initiative.
Genome-… and Alzheimer's disease and GWAS of baseline cerebrospinal fluid biomarkers and …

… in Alzheimer’s disease (AD) genetic studies. Although there … genetic studies of AD
endophenotypes. We performed sex-stratified and sex interaction genetic analyses of CSF …

… of Alzheimer's disease (AD) could be used as an enrichment tool for clinical development
of therapies. This study evaluated the prognostic performance of a genetics-based biomarker …

… biomarker pairs and brain differential gene expression analysis. We found a significant genetic
overlap between CSF and plasma biomarkers… of these biomarkers, when genetic variants …

… Manhattan plot from a study by Bellenguez and colleagues 16 showing the identified genetic
loci associated with Alzheimer disease in non-Hispanic white individuals. P values are two-…

… fluid biomarkers and neurofibrillary pathology, into a genetic risk profile may aid in the
selection of individuals at high risk and the prediction of future cognitive decline. As with …