Emerging isothermal amplification technologies for microRNA biosensing: Applications to liquid biopsies

G Gines, R Menezes, W Xiao, Y Rondelez… - Molecular Aspects of …, 2020 - Elsevier
… miRNA biomarkers from a single, usually precious liquid biopsy sample. Overall, miRNA
detection technologies adapted to liquid biopsies should present high sensitivity and specificity, …

Liquid biopsies: Potential and challenges

I Heidrich, L Ačkar… - … Journal of Cancer, 2021 - Wiley Online Library
… by micromanipulation or DEPArray technology, but it usually requires sufficiently high
starting CTC concentrations. For DNA analysis of single cells, whole genome amplification (WGA) …

[HTML][HTML] Liquid biopsy: current technology and clinical applications

M Nikanjam, S Kato, R Kurzrock - Journal of hematology & oncology, 2022 - Springer
Liquid biopsies are increasingly used for cancer molecular profiling that enables a precision
… This review will focus on current technologies and clinical applications for liquid biopsies. …

[HTML][HTML] Emerging concepts in liquid biopsies

S Perakis, MR Speicher - BMC medicine, 2017 - Springer
… and in light of technological limitations. Finally, we discuss whether liquid biopsies are ready
to be … TAm-Seq (tagged amplicon deep sequencing) amplifies entire genes by tiling short …

Liquid biopsies

E Lianidou, K Pantel - Genes, Chromosomes and Cancer, 2019 - Wiley Online Library
Liquid biopsy is based on minimally invasive blood tests and … Liquid biopsy approaches
include the analysis of circulating … The major advantage of liquid biopsy analysis is that it is …

[HTML][HTML] Sensitivity, specificity, and accuracy of a liquid biopsy approach utilizing molecular amplification pools

J Garcia, N Kamps-Hughes, F Geiguer, S Couraud… - Scientific reports, 2021 - nature.com
… of liquid biopsies as the standard of care in cancer treatment. The accuracy of liquid biopsy
… Publications have reported excellent agreement between cfDNA liquid biopsy testing and …

Circulating tumor DNA and liquid biopsy: opportunities, challenges, and recent advances in detection technologies

L Gorgannezhad, M Umer, MN Islam, NT Nguyen… - Lab on a Chip, 2018 - pubs.rsc.org
… Recent advances in ctDNA analysis methods will potentially lead to the development of a
liquid biopsy tool for the diagnosis, prognosis, therapy response monitoring, and tracking the …

[HTML][HTML] Recent advances in liquid biopsy technologies for cancer biomarker detection

N Soda, K Clack, MJA Shiddiky - Sensors & Diagnostics, 2022 - pubs.rsc.org
… PCR-based techniques are easy to operate with minimum cost for amplification of nucleic
acids. Over the past years, several PCR based strategies have been described notably, custom…

Recent advances in liquid biopsy in precision oncology research

Y Sato, R Matoba, K Kato - Biological and Pharmaceutical Bulletin, 2019 - jstage.jst.go.jp
… Massive parallel deep sequencing is the most feasible current approach to liquid biopsy. An
… PCR amplification. After PCR amplification, a consensus sequence for the amplified DNA …

[HTML][HTML] Latest development of liquid biopsy

AHK Cheung, C Chow, KF To - Journal of thoracic disease, 2018 - ncbi.nlm.nih.gov
… in liquid biopsy at the present moment. The clinical utility of many of the tests derived from
liquid biopsy … This review provides an overview of the concept of liquid biopsy, its clinical …