… , and validate key findings with neutralization assays. We find … in antibody escape: for
instance, at a single residue targeted by two antibodies, some mutations escape both antibodies …

… spike protein also carries crucial neutralizing epitopes. Here, … neutralizing capacity of
convalescent-phase COVID-19 sera. We report that a combination of two neutralizing antibodies …

… Finally, the emergence of antibody-resistant SARS-CoV-2 variants that might limit the … To
select SARS-CoV-2 S variants that escape neutralization by antibodies, we used a recently …

… glycoprotein (S), the target for neutralizing antibodies, single B cells were sorted from a …
prevented viral neutralization escape from RBD-directed MAbs. These data suggest that antibody …

… of two blocked neutralization escape. Interestingly, in mice the neutralization escape mutant
… that shows plasticity may have limitations for preventing neutralization escape during in vivo …

… Potential limitations of our work include the low number of sera analysed from vaccine
recipients and convalescent individuals, and the lack of characterization of cellular immunity, …

… antibody adsorptions and virus-entry assays, we found evidence in three subjects of neutralizing
antibody (… ∶50 (IC 50 ) selecting for virus escape. In each of the subjects, Nabs targeted …

… with increasing contents of escape variants as antibody pressure is elevated. Sequencing
of bulk virus cultures therefore has limitations in defining escape mutants at early stages of …

… The role of neutralizing antibodies (nAbs) in controlling disease progression is unclear. …
During prolonged CTL absence, neutralization-resistant virus mutants were selected in …

… to viral escape from neutralization and understanding their … Human monoclonal antibodies
HC84-1 and HC84-27 target … neutralization escape was yet observed for these antibodies. …