[HTML][HTML] Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain

AK Wheatley, P Pymm, R Esterbauer, MH Dietrich… - Cell Reports, 2021 - cell.com
… These RBD antibodies ameliorate SARS-CoV-2 infection in mice … antibody recognition
and neutralization highlights both potent single antibodies and stereotypic classes of antibodies

[HTML][HTML] The impact of receptor-binding domain natural mutations on antibody recognition of SARS-CoV-2

C Li, X Tian, X Jia, J Wan, L Lu, S Jiang, F Lan… - … and Targeted Therapy, 2021 - nature.com
… Such mutation rate is comparable to that of SARS-CoV-2 S1 (… efficacy of anti-SARS-CoV-2
antibodies, we expressed and … during the first 4 months of SARS-CoV-2 outbreak. All RBDs …

[HTML][HTML] Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies

M Yuan, H Liu, NC Wu, IA Wilson - Biochemical and biophysical research …, 2021 - Elsevier
… of the antibody response against SARS-CoV-… antibody recognition of the SARS-CoV-2
RBD. Three major epitopes on the RBD are recognized by the currently characterized SARS-CoV-…

[HTML][HTML] Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition

AJ Greaney, TN Starr, P Gilchuk, SJ Zost, E Binshtein… - Cell host & …, 2021 - cell.com
… The coronavirus disease 2019 (COVID-19) pandemic has … in antibody therapeutics
and vaccines that induce antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-…

[HTML][HTML] Defining a highly conserved cryptic epitope for antibody recognition of SARS-CoV-2 variants

A Hao, W Song, C Li, X Zhang, C Tu, X Wang… - … and Targeted Therapy, 2023 - nature.com
… and broadly neutralizing antibodies. We first explored whether a previously reported
bispecific single-domain antibody bn03 could resist the immune escape of the SARS-CoV-2 …

[HTML][HTML] Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein

N Suryadevara, S Shrihari, P Gilchuk, LA VanBlargan… - Cell, 2021 - cell.com
… infection of authentic SARS-CoV-2 and recombinant VSV/SARS-CoV-2 viruses. We …
SARS-CoV-2 S neutralization escape variants. Mechanistic studies showed that these antibodies

Genetic and structural basis for recognition of SARS-CoV-2 spike protein by a two-antibody cocktail

J Dong, SJ Zost, AJ Greaney, TN Starr, AS Dingens… - BioRxiv, 2021 - biorxiv.org
… to understand the molecular basis for immune recognition of SARS-CoV-2 spike (S) … for
SARS-CoV-2 neutralization, we determined the structures of two human monoclonal antibodies

SARS-CoV-2 neutralizing antibodies for COVID-19 prevention and treatment

D Li, GD Sempowski, KO Saunders… - Annual review of …, 2022 - annualreviews.org
… vary according to recognition epitopes. Several potent … that have antibody-escape mutations
and the potential for antibody-… representative SARS-CoV-2 neutralizing antibodies that have …

[HTML][HTML] Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies

CO Barnes, AP West, KE Huey-Tubman… - Cell, 2020 - cell.com
… Fabs, revealing recognition of both S1 A and RBD epitopes on SARS-CoV-2 … SARS-CoV-2
spike mutations. Overall, our studies structurally define a recurrent anti-SARS-CoV-2 antibody

[HTML][HTML] Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses

Y Chen, X Zhao, H Zhou, H Zhu, S Jiang… - Nature Reviews …, 2023 - nature.com
… Moreover, S309 can broadly neutralize sarbecoviruses, including all currently identified
SARS-CoV-2 VOC, as the epitope sequences recognized by S309 are highly conserved among …