… tune their properties for bio-molecule interaction and biological … mode of biomolecule
interactions and anticancer activity 19,… the binding and cytotoxic properties of metal complexes 21 . …

… Cu complexes were potential candidates for anticancer action and therefore deserve to be
… properties such as biomolecular interactions, antioxidant and anticancer properties as well …

… property as well as anticancer activity. Thus, we have synthesised the Pt(II) complexes [Pt
(TEEDA)Cl 2 ]; 1 and [Pt (TEEDA)(H 2 O) 2 ] 2+ ; 2, which is transformed to complex [Pt (TEEDA…

… the anticancer properties of these compounds are due to the covalent binding to DNA. In
addition to DNA binding, the platinum drugs bind and interact … complex anticancer mechanisms …

… Their biomolecular interactions with BSA and DNA were executed by spectroscopic methods…
their cytototoxic property was tested by the MTT assay. In vitro biomolecular interactions of Pt…

… The interaction of the compounds with calf thymus DNA (CT-DNA) has been estimated by …
The binding properties of the free ligand and its complexes with bovine serum albumin (BSA) …

… The synthesis of Cu(II)(pbzH)Cl 2 has been described [23], [24], but the complex has not
previously been studied for medicinal properties. However, the anticancer activity of metal-pbzH …

… anticancer agents that exhibit antitumour properties against … the mechanism of antitumour
properties of the metallocenes, … characterized platinum-based anticancer drugs, the active …

… superior anticancer potency than others. Thus, the complex (1) may contribute as potential
anticancer agent due to its unique interaction mode with DNA.GRAPHICAL ABSTRACT …

… outstanding antiproliferative properties The discovery of the anticancer properties of cisplatin
… , the kinetics of hydrolysis, and its specific reactivity toward biomolecules in comparison to …