… LPS and TNF-α with distinct kinetics, at 6 and 12–24 h, respectively. Using macrophages
derived from the TNF-α … of TNF-α. In macrophages from STAT-1 knockout mice, neither LPS nor …

… tuberculosis antigens can enter the MHC class I antigen processing pathway in human
macrophages through an alternate pathway, that does not require traffic through the classic ER-…

… The antigen processing phenotype of mice devoid of all … -γ (IFN-γ) or tumor necrosis
factor-α (TNF-α) stimulation, the three … in antigen processing as well as these novel functions. …

… many examples of inflammatory amplification mediated by TNF-α, in an Ag-… TNF expression
by the CD8 + T cells to the observed tissue injury. As such, we developed K d -restricted TNF-…

… ], supporting the notion that correct antigen processing requires the incorporation of these two
… complexes are, in most instances, more efficient than SP in generating antigenic peptides. …

… their Tcell stimulation and MHC II trafficking, and probably also their antigen processing,
functions while the other, the microglia, maintain their antigen presentation potential. …

… of the antigen can be impaired by several ways. Hence in spite of the existence of antigenic
… of MHC class I antigens, and of the components of the antigen processing and presentation …

… Here, we document the expression of antigen processing … cell surface human leukocyte
antigen (HLA) expression on … IFN)α/β because IFNα/β-neutralizing antibodies completely prevent …

… in antigen processing, LMP2 and presentation TAP1, play pivotal roles in defective viral antigen
processing resulting … The fact that IFN-γ and TNF-α levels were significantly higher in the …

… The pathways of antigen processing and presentation have recently been extensively
reviewed 4,14 and, therefore, in this Review we focus on aspects of antigen processing and …