Antimalarial activity: the search for marine-derived natural products with selective antimalarial activity

AD Wright, GM König, CK Angerhofer… - … of Natural Products, 1996 - ACS Publications
… ), two of which were new natural products (24 and 25), and one of which, axisonitrile-3 (22),
had potent in vitro antimalarial activity and no detectable cytotoxic properties, were isolated. …

[HTML][HTML] Antimalarial natural products: a review

F Mojab - Avicenna journal of phytomedicine, 2012 - ncbi.nlm.nih.gov
… The compounds were assayed in an in vitro system for antimalarial activity against
chloroquine-susceptible and chloroquine-resistant strains and their antimalarial activity against P. …

Antimalarial activity of natural and synthetic prodiginines

K Papireddy, M Smilkstein, JX Kelly… - Journal of medicinal …, 2011 - ACS Publications
… Herein we describe the in vitro antimalarial activity of four natural (IC 50 = 1.7–8.0 nM) and …
terminal nonalkylated pyrrole ring of natural prodiginines and had diminished activity (IC 50 > …

Antimalarial activity of natural product extracts from Papua New Guinean and Australian plants against Plasmodium falciparum

LS Fernandez, MF Jobling… - … of Natural Product …, 2008 - Wiley Online Library
natural product extract library of over 40 000 samples, 794 plant extracts from biota collected
from PNG and Australia were chosen to screen for antimalarial activity. … biological activity as …

Antimalarial activity of plant metabolites

WH Pan, XY Xu, N Shi, SW Tsang… - International Journal of …, 2018 - mdpi.com
… (Araceae), showed antimalarial activities of 1.5 and 1.4 µM … on natural products possessing
antimalarial activity. … plant-derived antiplasmodial active natural compounds up to the year …

Antiplasmodial natural products: an update

N Tajuddeen, FR Van Heerden - Malaria journal, 2019 - Springer
… Therefore, there is an urgent need to discover new anti-malarial drugs. This article reviews
the literature on natural products with antiplasmodial activity that was reported between 2010 …

Design of antimalarial agents based on natural products

J Jampilek - Current Organic Chemistry, 2017 - ingentaconnect.com
… and synthetic acridones demonstrated a wide spectrum of biological activities, but only limited
antimalarial activity (acridone, 44, IC50 = 2.0 M against P. falciparum D6 and IC50 = 2.5 M …

[图书][B] Antimalarial natural products

DGI Kingston, MB Cassera - 2022 - Springer
… The key to quinine’s antimalarial activity is its ability to inhibit … its antimalarial activity is
pH-dependent, with a loss of activity as … may be a contributing factor to its decreased activity [86]. …

[HTML][HTML] Natural products as sources of antimalarial drugs

PF Uzor, VD Prasasty, CO Agubata - … -based Complementary and …, 2020 - ncbi.nlm.nih.gov
… In this special issue, we intend to focus on recent studies dealing with the antimalarial
activity of natural products (including extracts and compounds) derived from medicinal plants, …

[PDF][PDF] Antimalarial natural products

SB Christensen, A Kharazmi - … Compounds from Natural …, 2001 - chemistry-chemists.com
… strong in vitro antimalarial activity and synergistically increases the activity of chloroquine.
Herveline D ( 36 ) also has a strong in vitro antimalarial activity but antagonises the activity of …