Characterization and time course of MPP+‐induced apoptosis in human SH‐SY5Y neuroblastoma cells

CP Fall, JP Bennett Jr - Journal of neuroscience research, 1999 - Wiley Online Library
… Multiple neurotransmitter synthesis by human neuroblastoma … A primate model of
parkinsonism: selective destruction of … to low doses of the parkinsonism-inducing neurotoxin 1-…

Novel neuroprotective mechanisms of pramipexole, an anti-Parkinson drug, against endogenous dopamine-mediated excitotoxicity

Y Izumi, H Sawada, N Yamamoto, T Kume… - European journal of …, 2007 - Elsevier
… Cultured mesencephalic cells were exposed to drugs for 24 h on 9 days in vitro. The cultures
were incubated in EMEM containing 10% horse serum without drugs for further 48 h and …

Acute mitochondrial and chronic toxicological effects of 1-methyl-4-phenylpyridinium in human neuroblastoma cells

SE Stephans, GW Miller, AI Levey, JT Greenamyre - Neurotoxicology, 2002 - Elsevier
… A human neuroblastoma cell line expressing the dopamine transporter (DAT) was utilized
to examine the effects of MPP + on acute physiologic responses and subsequent cell death. …

[HTML][HTML] Evaluation of the anti-apoptotic and anti-cytotoxic effect of epicatechin gallate and edaravone on SH-SY5Y neuroblastoma cells

M Shokrzadeh, H Javanmard, GG Zadeh… - Basic and Clinical …, 2019 - ncbi.nlm.nih.gov
… of epicatechin and edaravone in combination with levodopa as anti-Parkinson drug (L-Dopa;)
on the proliferation and apoptosis in SH-SY5Y neuroblastoma cell line affected by 6-OH …

Effects of 6-hydroxydopamine on mitochondrial function and glutathione status in SH-SY5Y human neuroblastoma cells

MA Tirmenstein, CX Hu, MS Scicchitano… - Toxicology in Vitro, 2005 - Elsevier
… SH-SY5Y human neuroblastoma cells were incubated with 6-hydroxydopamine (6-OHDA)
for 4 and 24 h to examine the mechanism of cell death and to determine the time-dependent …

Dopamine exacerbates mutant Huntingtin toxicity via oxidative-mediated inhibition of autophagy in SH-SY5Y neuroblastoma cells: Beneficial effects of anti-oxidant …

C Vidoni, A Castiglioni, C Seca, E Secomandi… - Neurochemistry …, 2016 - Elsevier
… se toxic to dopaminergic human neuroblastoma SH-SY5Y cells… of autophagy underlies the
parkinsonism in HD patients. Our … the death of dopaminergic human neuroblastoma SH-SY5Y …

SNJ‐1945, a calpain inhibitor, protects SH‐SY5Y cells against MPP+ and rotenone

VH Knaryan, S Samantaray, S Park… - Journal of …, 2014 - Wiley Online Library
parkinsonism. However, the mechanisms of these degenerative pathways are not well
understood. To unravel these mechanisms SH-SY5Y neuroblastoma … in human neuroblastoma

Molecular and clinical pathways to neuroprotection of dopaminergic drugs in Parkinson disease

AHV Schapira - Neurology, 2009 - AAN Enterprises
… Rat pheochromocytoma PC-12 cells and dopaminergic human neuroblastoma SH-SY5Y
cells subjected to serum and nerve growth factor withdrawal exhibit death by apoptosis. …

Terminally differentiated SH-SY5Y cells provide a model system for studying neuroprotective effects of dopamine agonists

SP Presgraves, T Ahmed, S Borwege, JN Joyce - Neurotoxicity research, 2003 - Springer
Antiparkinsonian agents that are direct DA agonists such as apomorphine (Grünblatt et al., …
The human neuroblastoma cell line SH-SY5Y, which was subcloned from the SK-N-SH cell …

Amyloid processing and signal transduction properties of antiparkinson‐antialzheimer neuroprotective drugs rasagiline and TV3326

MBH Youdim, T Amit, O BAR‐AM… - Annals of the New …, 2003 - Wiley Online Library
… )-B inhibitor antiparkinson drug that exerts neuroprotective … human SH-SY5Y neuroblastoma
and rat PC12 cells.7 Our findings provide evidence, for the first time, that these novel drugs