SARS-CoV-2 antiviral therapy

K Tao, PL Tzou, J Nouhin, H Bonilla… - Clinical microbiology …, 2021 - Am Soc Microbiol
… CTC-445.2d is a dimeric ACE2 mimic that has been shown to protect SARS-CoV-2-infected …
supports a role for IFNs in protection against SARS-CoV-2. SARS-CoV-2 infection has been …

[HTML][HTML] Oral antivirals for the prevention and treatment of SARS-CoV-2 infection

V Soriano, C De-Mendoza, B Edagwa, A Treviño… - AIDS …, 2022 - ncbi.nlm.nih.gov
… As a complementary intervention, specific SARS-CoV-2 antivirals may provide protection
in individuals at high risk for contagion and/or for developing severe COVID-19. Waning of …

Mechanisms of antiviral immune evasion of SARS-CoV-2

DK Beyer, A Forero - Journal of molecular biology, 2022 - Elsevier
… Although either IFNα/β or IFN-λ can confer antiviral protection, the tissue and dose of …
SARS-CoV-2 inhibits the expression and distribution of IFNLR1, which confers antiviral protection

Potent antiviral effect of silver nanoparticles on SARS-CoV-2

SS Jeremiah, K Miyakawa, T Morita, Y Yamaoka… - Biochemical and …, 2020 - Elsevier
antiviral properties and are presumed to inhibit SARS-CoV-2. … agent against SARS-CoV-2,
we evaluated the antiviral effect of … protect VeroE6/TMPRSS2 cells from SARS-CoV-2 infection …

SARS-CoV-2 Mpro inhibitors with antiviral activity in a transgenic mouse model

J Qiao, YS Li, R Zeng, FL Liu, RH Luo, C Huang… - Science, 2021 - science.org
SARS-CoV-2 M pro (11–13) and our cocrystal structures of SARS-CoV-2 M pro in complex
with the approved antivirals … ’ cellular antiviral activity was examined by a cell protection assay…

Antibacterial and antiviral high-performance nanosystems to mitigate new SARS-CoV-2 variants of concern

S Tiwari, S Juneja, A Ghosal, N Bandara… - Current Opinion in …, 2022 - Elsevier
protect and be sterilized against SARS-CoV-2 [43,44]. Even biopolymers in nano-assemblies
have been reported to generate potential antiviral … can neutralize the SARS-CoV-2 (Figure 3…

Potential antiviral options against SARS-CoV-2 infection

A Ianevski, R Yao, MH Fenstad, S Biza, E Zusinaite… - Viruses, 2020 - mdpi.com
… Here, we developed a neutralization assay using SARS-CoV-2 … of SARS-CoV-2-infected
patients. We also screened 136 safe-in-man broad-spectrum antivirals against the SARS-CoV-2 …

Divergent trajectories of antiviral memory after SARS-CoV-2 infection

A Tomic, DT Skelly, A Ogbe, D O'Connor… - Nature …, 2022 - nature.com
… -2, our findings raise the possibility that people with asymptomatic SARS-CoV-2 infection
may have less protection from re-infection after primary infection. The timing of infection onset …

SARS-CoV-2: An update on potential antivirals in light of SARS-CoV antiviral drug discoveries

HA Elshabrawy - Vaccines, 2020 - mdpi.com
… Passive transfer of sera from mice that were previously infected with SARS-CoV protected
naïve mice from SARS-CoV intranasal challenge [23]. Furthermore, recombinant protein …

RIG-I-induced innate antiviral immunity protects mice from lethal SARS-CoV-2 infection

S Marx, BM Kümmerer, C Grützner, H Kato… - … Therapy-Nucleic Acids, 2022 - cell.com
… -term antiviral protection against SARS-CoV-2 infection, and it has great potential as a
broad-spectrum approach to constrain the spread of newly emerging viruses until virus-specific …