The AP-1 site and MMP gene regulation: what is all the fuss about?

U Benbow, CE Brinckerhoff - Matrix biology, 1997 - Elsevier
… Despite this differential expression, there exists a high degree of similarity among the cis-…
differential expression Fos and Jun family members (Mauviel et al., 1996). Inhibition of MMP-1

Separation of v-Src-induced mitogenesis and morphological transformation by inhibition of AP-1.

MC Frame, K Simpson, VJ Fincham… - Molecular biology of the …, 1994 - Am Soc Cell Biol
… an approach similar to that of other groups to inhibit AP-1 by expression of an interfering
mutant of c-… Differential expression of Rous sarcoma virus-specific transformation parameters in …

Differential effects of transforming growth factor-β1 on the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in young and old human …

DR Edwards, KJ Leco, PP Beaudry, PW Atadja… - Experimental …, 1996 - Elsevier
… with repression of MMP transcription by TGF[3-1 (Kerr et al. 1990). We, therefore, assessed
the relative levels in young and old cells of AP1 and TIE-binding factors, along with another …

Differential Inhibition of Ca2+ Channels by α2-Adrenoceptors in Three Functional Subclasses of Rat Sympathetic Neurons

C Li, JP Horn - Journal of neurophysiology, 2008 - journals.physiology.org
… Although insensitive to NE, both the AP shoulder and AHP duration were inhibited in an
identified, TEA+-treated, vasoconstrictor neuron after bath-application of 10 μM Oxo-M. Arrows …

Inhibition of phorbol ester‐induced monocytic differentiation by dexamethasone is associated with down‐regulation of c‐fos and c‐jun (AP1)

R Hass, M Brach, S Kharbanda, G Giese… - Journal of cellular …, 1991 - Wiley Online Library
… of both genes is inhibited at the transcriptional level by … to -20) of the promoter that contains
the AP-1 binding site. This … cytic differentiation by inhibiting activation of the AP-1 site. …

[PDF][PDF] Repression of T-cell function by thionamides is mediated by inhibition of the AP-1/NFAT pathway and is associated with a common structure

M Humar, H Dohrmann, P Stein, N Andriopoulos… - Molecular …, 2007 - Citeseer
inhibit IL-2 cytokine expression, proliferation and the activation (CD69 expression) of primary
human T lymphocytes. Inhibition … transcription factors activator protein 1 (AP-1) and nuclear …

Quassinoid inhibition of AP-1 function does not correlate with cytotoxicity or protein synthesis inhibition

JA Beutler, MI Kang, F Robert, JA Clement… - Journal of natural …, 2009 - ACS Publications
… Moreover, a significant differential in sensitivity was shown in … samples that inhibit the function
of the transcription factor AP-1, we … for AP-1, it was also not well correlated with cell growth …

Differential sensitivity of cancer cells to inhibitors of the epidermal growth factor receptor family

PC Bishop, T Myers, R Robey, DW Fry, ET Liu… - Oncogene, 2002 - nature.com
… Using these and other receptor kinase inhibitors, we sought to define a cellular model to …
the differential sensitivity to HER1/HER2 inhibitors. HER1/HER2 specific inhibitors mediate a G1 …

Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1

R Kleemann, A Hausser, G Geiger, R Mischke… - Nature, 2000 - nature.com
… to non-AP-1-related activities, we studied the effect of MIF on the cell-cycle inhibitor p27 Kip1
, … For [35S]rMIF experiments, cells were subjected to subcellular fractionation by differential

Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi

YJ Wang, J Wang, HQ Sun, M Martinez, YX Sun… - Cell, 2003 - cell.com
… that the Golgi AP-1 adaptor complex directly binds PI(4)P. Furthermore, PI(4)P, but not PIP2,
is required for AP-1 recruitment to … However, it does not act as a dominant negative inhibitor. …