NF-κB and AP-1 connection: mechanism of NF-κB-dependent regulation of AP-1 activity

S Fujioka, J Niu, C Schmidt, GM Sclabas… - … and cellular biology, 2004 - Am Soc Microbiol
… mechanism by which the NF-κB signal pathway regulates AP-1 activity, we stimulated both
… , which strongly activates both NF-κB and AP-1 by inducing reactive oxygen species (ROS) (…

Activator protein 1 (AP-1)–and nuclear factor κB (NF-κB)–dependent transcriptional events in carcinogenesis

TC Hsu, MR Young, J Cmarik, NH Colburn - Free Radical Biology and …, 2000 - Elsevier
AP-1 and NF-κB, inducible by tumor promoters or oxidative … We further demonstrated
that AP-1 and NF-κB are both … NF-κB proteins or extracellular signal–regulated kinase (ERK…

[PDF][PDF] Oxidative stress and gene expression: the AP-1 and NF-kappaB connections

M Karin, T Takahashi, P Kapahi, M Delhase… - BIOFACTORS …, 2001 - academia.edu
… In conclusion, we find little role for oxidants in the positive regulation of NF-κB, but through
inhibition of NF-κB which protects cells from apoptosis, oxidants can sensitize cells to …

NF-κB, AP-1, Zinc-deficiency and aging

G Herbein, A Varin, T Fulop - Biogerontology, 2006 - Springer
… depletion of Zn, both NF-κB and AP-1 signallings are altered in … A supplementation of Zn
restored both NF-κB and AP-1 … present knowledge on NF-κB and AP-1 activation and underline …

Regulation of the transcription factors NF-κB and AP-1 by redox changes

M Meyer, HL Pahl, PA Baeuerle - Chemico-biological interactions, 1994 - Elsevier
NF-rB ROIs produced in response to PMA serve as second messengers [14,15]. Since NF-rB
and AP-1 … The DNA-binding and transactivating potential of AP-1 and NF-rB was assayed in …

[HTML][HTML] Enhanced NFκB and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer

Y Zhou, C Yau, JW Gray, K Chew, SH Dairkee… - BMC cancer, 2007 - Springer
AP-1 and NFκB DNA-binding and transcriptional activities, were studied to compare tamoxifen
effects on NFκB and AP-1 … signifying upregulated NFκB and AP-1 transcriptional activity in …

[HTML][HTML] Tubular NF-κB and AP-1 activation in human proteinuric renal disease

SA Mezzano, M Barría, MA Droguett, ME Burgos… - Kidney international, 2001 - Elsevier
… On the whole, our results show that a tubular overactivation of NF-κB and AP-1 and a …
Increased activation of solely NF-κB and/or AP-1 may merely indicate the response of …

NFκB and AP-1 mediate transcriptional responses to oxidative stress in skeletal muscle cells

LZH Zhou, AP Johnson, TA Rando - Free Radical Biology and Medicine, 2001 - Elsevier
… been focused on the transcriptional regulators NFκB and AP-1 because they have been found
… The goal of the present studies was to test whether NFκB and AP-1 are induced in muscle …

Liver NFκB and AP1 DNA binding in obese patients

LA Videla, G Tapia, R Rodrigo, P Pettinelli, D Haim… - …, 2009 - Wiley Online Library
… Our aim was to assess nuclear factor-κB (NF-κB) and activating protein-1 (AP-1) activation
and Toll-like receptor 4 (TLR4) expression as signaling mechanisms related to liver injury in …

[HTML][HTML] Role of oxidants and antioxidants in the induction of AP-1, NF-κB, and glutathione S-transferase gene expression

R Pinkus, LM Weiner, V Daniel - Journal of Biological Chemistry, 1996 - ASBMB
… of AP-1 and NF-κB … of AP-1 and GST Ya gene expression by PDTC was inhibited by N-acetyl
cysteine and GSH. The present findings do not support the notion that the induction of AP-1