… Recently, novel mechanistic pathways of endothelial dysfunction and arterial stiffness in HF
… We therefore discuss the role of vascular function measures as potential targets for new HF …

… of vascular elastin and collagen fibres. Several different types of MMP exist in the vascular
wall, but in relation to arterial stiffness, … associated with increased arterial stiffness. In addition, …

… atheromatous cardiovascular disease is falling, pathology associated with arterial stiffening
… for all clinicians involved in care of patients with cardiovascular disease will become vital. …

… cardiovascular disease and its risk factors, as in our population (3,4). Our findings of increased
arterial stiffness and endothelial dysfunction … , by precipitating vascular dysfunction, might …

… represent advanced disease that should be detected earlier. Because the vascular
disease may have its origin in endothelial dysfunction, which has a profound influence on the …

… are major contributors to arterial stiffening, 60 an independent cardiovascular risk factor. A …
an increase in arterial stiffness. In our study, the increase in arterial stiffness in WT HFHS mice …

… Vascular stiffening of the large arteries is a common feature … disorders such as hypertension,
diabetes, and renal disease. … coupling disease in which stiffness of both heart and arteries …

… of endothelial dysfunction and low-grade inflammation is associated with arterial stiffening in
… have measured biomarkers of endothelial dysfunction, low-grade inflammation, and arterial …

… baseline CRP levels predict future cardiovascular events. Each of … that assessments of these
vascular markers are not mutually … the role of arterial stiffness, endothelial dysfunction and …

… of the large elastic arteries and endothelial dysfunction … Both arterial stiffness and
vascular endothelial dysfunction … Targeting arterial stiffening and endothelial dysfunction is …