This article reviews developments in artificial intelligence (AI) technologies and their current and prospective applications in clinical psychological practice. Some of the principal AI assisted activities reviewed include clinical training, treatment, psychological assessment, and clinical decision making. A concept for an integrated AI-based clinician system is also introduced. Issues associated with AI in the context of clinical practice, the potential for job loss among mental health professionals, and other ramifications associated with the advancement of AI technology are discussed. The advancement of AI technologies and their application in psychological practice have important implications that can be expected to transform the mental health care field. Psychologists and other mental health care professionals have an essential part to play in the development, evaluation, and ethical use of AI technologies.