Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index

W Wen, W Zheng, Y Okada, F Takeuchi… - Human molecular …, 2014 - academic.oup.com
… We identified four novel BMI-associated loci near the KCNQ1 (rs2237892, P = 9.29 × 10 −…
-associated loci initially identified in European-ancestry populations, we confirmed eight loci at …

European bone mineral density loci are also associated with BMD in East-Asian populations

U Styrkarsdottir, BV Halldorsson, DF Gudbjartsson… - PLoS …, 2010 - journals.plos.org
… The previously reported GWS loci in European populations that we tested were 1p36 (… loci
associated with BMD in East-Asians in this study (FDR<0.05). Markers at ten loci associated

Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations

Y Okada, X Sim, MJ Go, JY Wu, D Gu, F Takeuchi… - Nature …, 2012 - nature.com
… , 8, 7 and 4 loci for blood urea nitrogen, … associated loci were associated with both serum
creatinine concentration and eGFRcrea, with the same landmark SNPs involved at each locus, …

Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations

K Tang, SM Ngoi, PC Gwee, JMZ Chua… - Pharmacogenetics …, 2002 - journals.lww.com
… Haplotype frequencies of the three high-frequency SNP loci present in our population.
The SNP loci in the haplotype are ordered as: SNP exon 12 1236—SNP exon 21 2677—SNP …

Evaluating marginal genetic correlation of associated loci for complex diseases and traits between European and East Asian populations

H Lu, T Wang, J Zhang, S Zhang, S Huang, P Zeng - Human Genetics, 2021 - Springer
… with many complex phenotypes in diverse populations. … of associated loci of phenotypes
across populations remains … in one population can be generalized to other populations or can …

Large-scale genome-wide association study of East Asians identifies loci associated with risk for colorectal cancer

Y Lu, SS Kweon, C Tanikawa, WH Jia, YB Xiang, Q Cai… - Gastroenterology, 2019 - Elsevier
… descent were also associated with CRC risk in East Asians. Furthermore, we identified 13
loci significantly associated with risk for CRC in Asians. Many of these loci contained genes …

A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease

Statistical genetics and bioinformatics Goel Anuj 1 2 … - Nature …, 2011 - nature.com
… variants were significantly associated with CAD risk in both the European and South Asian
populations in the current study, indicating the importance of the genes associated with CAD …

Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations

Y Okada, M Kubo, H Ohmiya, A Takahashi… - Nature …, 2012 - nature.com
… are greater in Asians than in Europeans when evaluated with the same BMI 13 . Thus, the
study of Asian populations might lead to the identification of new obesity-associated loci and …

Common variant in 6q26-q27 is associated with distal colon cancer in an Asian population

R Cui, Y Okada, SG Jang, JL Ku, JG Park, Y Kamatani… - Gut, 2011 - gut.bmj.com
… −9 , OR of 1.28) that was significantly associated with distal colon cancer. We also replicated
locus in SLC22A3 that contributes to the risk of distal colon cancer in an Asian population. …

A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits

YS Cho, MJ Go, YJ Kim, JY Heo, JH Oh, HJ Ban… - Nature …, 2009 - nature.com
… To date, most of these studies have focused on samples of European origin, and it
remains unclear whether the same loci contribute to trait associations in Asian populations. …