Intraindividual variability of aldosterone concentrations in primary aldosteronism: implications for case detection

N Yozamp, GL Hundemer, M Moussa, J Underhill… - …, 2021 - Am Heart Assoc
… It is often advised that screening for primary aldosteronism be conducted after … day,
characteristics of the assays (the type of assay for aldosterone and the lower limit of the renin assay), …

An individualized approach to the evaluation and management of primary aldosteronism

A Vaidya, CD Malchoff, RJ Auchus… - Endocrine Practice, 2017 - Elsevier
… For the purposes of this article on primary aldosteronism (PA), … of nongenetic patient
characteristics to optimize care of the … assays are being phased out in favor of renin mass assay, …

High efficiency of the aldosterone-to-renin ratio in precisely detecting primary aldosteronism

W Gan, W Lin, J Ouyang, Y Li, D Chen, Z Yao… - Journal of Human …, 2019 - nature.com
… The aldosterone-to-renin ratio (ARR) is extensively used for primary aldosteronism
detection. Chemiluminescence immune assay (CLIA) is newly applied in aldosterone and renin …

Plasma and urine aldosterone to plasma renin activity ratio in the diagnosis of primary aldosteronism

G Bernini, A Moretti, C Orlandini, P Berti… - Journal of …, 2008 - journals.lww.com
… Therefore, we analyzed our data both with the PRA levels detected effectively in the
assay and with PRA set at 0.2 ng/ml/h for values below this detection limit. Although the ALD/PRA …

Progress in aldosteronism: a review of the prevalence of primary aldosteronism in pre-hypertension and hypertension

G Piaditis, A Markou, L Papanastasiou… - European Journal of …, 2015 - academic.oup.com
Primary aldosteronism (PA) is the most common form of endocrine hypertension secondary
to excessive or inappropriately elevated aldosterone production from the adrenals that is …

The aldosterone–renin ratio in screening for primary aldosteronism

M Stowasser, RD Gordon - The Endocrinologist, 2004 - journals.lww.com
… Recognition that primary aldosteronism (PAL) is a common specifically treatable form of …
, and on access to reliable and reproducible assays for renin and aldosterone. Even then, …

Diagnostic accuracy of the aldosterone–to–active renin ratio for detecting primary aldosteronism

S Pilz, MH Keppel, C Trummer… - Journal of the …, 2019 - academic.oup.com
Context The aldosterone–to–active renin ratio (AARR) is the recommended screening test
for primary aldosteronism (PA), but prospective study data on its sensitivity and specificity are …

Novel approach to establishing an aldosterone: renin ratio cutoff for primary aldosteronism

AA Leung, DJ Orton, A Chin, H Sadrzadeh… - Hypertension, 2017 - Am Heart Assoc
… We described the prevalence of primary aldosteronism in our … after the introduction of the
new assay. During the initial portion … direct renin concentration assay. A highly probable case of …

Renin-angiotensin-aldosterone system triple-A analysis for the screening of primary aldosteronism

J Burrello, F Buffolo, O Domenig, M Tetti, A Pecori… - …, 2020 - Am Heart Assoc
Primary aldosteronism is recognized as the most frequent … mass spectrometry diagnostic
assay that allows simultaneous … (33 patients with confirmed primary aldosteronism and 77 with …

Diagnosis and treatment of primary aldosteronism

GPD Rossi - Reviews in Endocrine and Metabolic Disorders, 2011 - Springer
… DRA assay has recently gained wide popularity and is currently replacing the PRA assay for
… respect to the two renin assays is that the DRA and PRA assay are differentially affected by …