… Conclusion In this review of candidate gene association studies, nearly one-third of gene-variant
cancer associations were statistically significant, with variants in genes encoding for …

… on using population-based association studies. Association studies identify variants, which
… Early association studies of cancers were based on the analysis of polymorphic variation in …

… Mutation screening in HPC probands and association … carried out for the putative prostate
cancer–susceptibility gene, PG1, … existence of a prostate cancer–susceptibility gene at 8p22-23…

… as credibility and strength of an association with cancer susceptibility. Five SNPs on five
genes with strong evidence of association were identified, including CYP1A1 rs1048943, EGF …

… The relevance of many low-penetrance genes in cancer susceptibility is supposed to be
very subtle. Several reviewed association studies revealed weaknesses in their design. …

… wide association studies (GWAS) on prostate cancer that include several common variants
associated with disease susceptibility 1… cancer and a variant refining the previously published …

… used in early association studies in cancer genetics and the … cancer, but important lessons
and ideas have also been derived from the experience of carrying out association studies …

… Genome-wide association studies (GWAS) have identified multiple common … cancer (PrCa),
but these explain less than one-third of the heritability. To identify further susceptibility alleles…

… Association Studies (GWAS) revealed novel genetic markers for breast cancer susceptibility…
But little is known about the risk factors and molecular events associated with breast cancer …

… cancer risk. The putative roles of ERCC1 gene polymorphisms in lung cancer susceptibility
… that these two ERCC1 polymorphisms were not associated with lung cancer susceptibility. …