… focus on drug repurposing, also known as drug repositioning. Drug repurposing involves …
new clinical indications, such that these drugs can be deployed clinically with greater speed …

… of candidate drug-disease relationships. Genetic-based association studies, including
GWAS, have proven to be effective for generating hypotheses related to drug repurposing 5,6 . …

… cohorts in drug association studies because drug … drug level and results from other recent
studies, 13, 26-28 we conducted an exploratory analysis to investigate associations of the drug …

… Over the past few years, large investments have been made in genome-wide association
studies (GWAS) with the expectation that some of these studies would lead to the identification …

… repurposed drugs could be brought into clinical practice within a shorter time-frame and at a
much reduced cost. Numerous computational approaches to drug … wide association studies (…

… Initial results on drug repurposing studies using network analysis are encouraging and
suggest directions for future development[7]. By integrating rheumatoid arthritis genetic findings …

… Lastly, we perform computational drug repurposing and … drug repurposing using our TWAS
results and identified clinically-relevant small molecule compounds that may be repurposed …

… Drug repurposing is an effective means for rapid drug discovery. The aim of this study was …
Literature-Wide Association Studies (LWAS) of PubMed to repurpose existing drugs for a rare …

… for drug repurposing (also known as drug repositioning), discuss the challenges faced by
the repurposing … Genome-wide association studies. There has been a large increase in the …

… We designed a 3-Step Medication-Wide Association Study Plus (… of drugs with a high
potential to be repurposed to delay and prevent AD/ADRD. Like genome-wide association studies (…