[HTML][HTML] Genome-wide association studies of brain imaging phenotypes in UK Biobank

LT Elliott, K Sharp, F Alfaro-Almagro, S Shi, KL Miller… - Nature, 2018 - nature.com
… of associations between single nucleotide polymorphisms and imaging phenotypes that …
Notable significant, interpretable associations include: iron transport and storage genes, …

An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank

SM Smith, G Douaud, W Chen, T Hanayik… - Nature …, 2021 - nature.com
… The X chromosome is typically understudied in GWASs, and many of the X chromosome
loci that we identify are now implicated in genetic associations with brain imaging phenotypes

Cross-ancestry genome-wide association studies of brain imaging phenotypes

J Fu, Q Zhang, J Wang, M Wang, B Zhang, W Zhu… - Nature Genetics, 2024 - nature.com
associations with similar effect sizes between ancestries. Loci of these associations were
shared with 15 brain-related non-imaging … genetic associations for brain imaging phenotypes in …

Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort

…, Alzheimer's Disease Neuroimaging Initiative - Neuroimage, 2010 - Elsevier
… whole brain strategy to systematically evaluate genetic effects on brain imaging phenotypes
for … Following quality control of the genotyping data, genome-wide association studies were …

[HTML][HTML] Phenotypic and genetic associations of quantitative magnetic susceptibility in UK Biobank brain imaging

C Wang, AB Martins-Bach, F Alfaro-Almagro… - Nature …, 2022 - nature.com
… of QSM-based imaging measures of multiple brain structures in … statistically significant
associations of 251 phenotypes with … Genome-wide associations relate magnetic susceptibility to …

Brain imaging as an approach to phenotype characterization for genetic studies of schizophrenia

JH Callicott, DR Weinberger - Psychiatric genetics: methods and reviews, 2003 - Springer
… ?; and 2) Once a brain imaging abnormality appears to be under significant genetic …
examination of brain imaging phenotypes currently under study. Functional brain imaging findings in …

A genome-wide association study of schizophrenia using brain activation as a quantitative phenotype

SG Potkin, JA Turner, G Guffanti, A Lakatos… - Schizophrenia …, 2009 - academic.oup.com
… Ancestry correction in genome-wide association studies: Comparison … brain imaging activation
patterns as the starting point in our analyses, based on the assumption that brain imaging

[HTML][HTML] Unsupervised deep representation learning enables phenotype discovery for genetic association studies of brain imaging

K Patel, Z Xie, H Yuan, SMS Islam, Y Xie, W He… - Communications …, 2024 - nature.com
… , brain measures for genome-wide association studies (GWAS) consisted of traditionally
expert-defined or software-derived image-derived phenotypes … derive brain imaging phenotypes

From phenotype to genotype: an association study of longitudinal phenotypic markers to Alzheimer's disease relevant SNPs

…, Alzheimer's Disease Neuroimaging Initiative - …, 2012 - academic.oup.com
Neuroimaging genetics is an emerging research field, where brain imaging is used as
quantitative phenotypes … To incorporate such SNP correlations in our association studies, we …

Detecting genetic associations with brain imaging phenotypes in Alzheimer's disease via a novel structured SCCA approach

L Du, K Liu, X Yao, SL Risacher, J Han, AJ Saykin… - Medical image …, 2020 - Elsevier
… between genetic factors and the structures or functions of the human brain. Sparse …
association identification method. To mine the complex genetic basis of brain imaging phenotypes, …