[HTML][HTML] Genetic predictors of testosterone and their associations with cardiovascular disease and risk factors: a Mendelian randomization investigation

CM Schooling, S Luo, SLA Yeung… - International journal of …, 2018 - Elsevier
genetic associations of variants in two gene regions (SHBG and JMJD1C) with several
cardiovascular risk factors … We assessed genetic associations with coronary artery disease (CAD) …

Sex-specific associations of testosterone and genetic factors with health span

X Zhao, S Liang, N Wang, T Hong… - Frontiers in …, 2021 - frontiersin.org
Genetic factors increased the HST risk, suggesting that participants with both high genetic
risk and abnormal testosterone … highlight the associations between testosterone and health …

Genetic determinants of serum testosterone concentrations in men

C Ohlsson, H Wallaschofski, KL Lunetta, L Stolk… - … genetics, 2011 - journals.plos.org
association study to examine the effects of common genetic … known risk factors such as age,
smoking, and BMI [19], [20]. … the genetic factors that affect serum testosterone concentrations …

Genetic influence on the association between bone mineral density and testosterone in Korean men

J Shin, J Sung, K Lee, YM Song - Osteoporosis International, 2016 - Springer
genetic factors that co-determine both testosterone and BMD may contribute to the association
… BMD and testosterone are influenced by environmental factors, the role of environmental …

SNPs associated with testosterone levels influence human facial morphology

J Roosenboom, K Indencleef, MK Lee… - … in genetics, 2018 - frontiersin.org
… The amount of circulating testosterone present in the body is the result of many factors, …
testosterone levels in adults. We observed associations with three of these SNPs in two genes: …

Using human genetics to understand the disease impacts of testosterone in men and women

…, Endometrial Cancer Association Consortium… - Nature medicine, 2020 - nature.com
… We note that our findings do not preclude an additional bi-directional effect of disease status
on testosterone or suggest that other factors are not important causal determinants of the …

Genomic predictors of testosterone levels are associated with muscle fiber size and strength

JPLF Guilherme, EA Semenova, OV Borisov… - European Journal of …, 2022 - Springer
testosterone levels have been identified in nonathletic populations. The aim of the present
study was to test the association of 822 testosterone-… serum testosterone, with genetic factors

Association of genetically predicted testosterone with thromboembolism, heart failure, and myocardial infarction: mendelian randomisation study in UK Biobank

S Luo, SLA Yeung, JV Zhao, S Burgess, CM Schooling - bmj, 2019 - bmj.com
… at Bonferroni corrected significance; or violation of the mendelian randomisation
assumption that the genetic variant should be unrelated to factors potentially confounding any …

Genetically predicted testosterone and cardiovascular risk factors in men: a Mendelian randomization analysis in the Guangzhou Biobank Cohort Study

J Zhao, C Jiang, TH Lam, B Liu… - International journal …, 2014 - academic.oup.com
… Here, we examined the association of testosterone with well-established CVD risk factors
and the … based on the association of genetic variants with testosterone in young men, when …

Mendelian randomization suggests non‐causal associations of testosterone with cardiometabolic risk factors and mortality

R Haring, A Teumer, U Völker, M Dörr, M Nauck… - …, 2013 - Wiley Online Library
… that the associations of serum testosterone concentrations with cardiometabolic risk factors
and mortality might … The triangulation of the associations between genetic instruments, serum …