… to osteoclasts than VPL and can be regarded as an osteoclast marker among bone cells. The
expression of VPL and CA I1 in osteoclasts is … In nonresorbing osteoclasts VPL and CA I1 …

… Carbonic anhydrase II and vacuolar H + -ATPases produce and transport protons, while
chloride channels provide a Cl − flux into the resorption site. These activities are required for …

… bone resorption, carbonic anhydrase II isoenzyme (CA II) and H+-ATPase, in osteoclasts from
four … CA II was present in most osteoclasts from normal, tl, op, and mib littermates and was …

… osteoclast differentiation. To study how CA II, which is crucial in proton generation in mature
osteoclasts, influences the osteoclast … to H()-ATPase of avian osteoclast ruffled membrane. …

… Carbonic anhydrase has been identified in osteoclasts by … of carbonic anhydrase in isolated
osteoclasts and compare it with values for red blood cells, No change in carbonic anhydrase …

… -type H+-ATPase inhibitor baf'domycin AI (baf. At) and the carbonic anhydrase II inhibitor
acetazolamide (AZ) on bone resorption and procathepsin L secretion of rat osteoclasts were …

… osteoclast acidification is dependent on carbonic anhydrase … Another important role of
carbonic anhydrase in osteoclasts is … V-ATPase is expressed in mononuclear osteoclasts along …

… , a highly conductive chloride channel, chloride bicarbonate exchangers, carbonic anhydrase
and accessory pumps; these serve to maintain the overall intra and extracellular ionic …

… It is reported that inhibition of VATPase-mediated proton release in osteoclasts could be
a trigger for apoptosis. Then, considering the present findings about suppressed proton …

… In osteoclast cytoplasm, carbonic anhydrase II generates the primary source of protons
for … differentiation and seems to be a component of the osteoclast plasma membrane V-ATPase. …