… Moreover, we discussed their involvement in autoimmune disorders associated to an …
approaches targeting Th17 transcriptional regulators in Th17-related autoimmune diseases. …

… in clinical practice for some of these autoimmune diseases. Given this onslaught of … cells
can provide TGF-β for IL-17 production, but more importantly promote Th17 cell differentiation …

… contribute to Th17 cell differentiation, plasticity and autoimmune disease susceptibility. (A)
The chromatin landscape of the human IL17A locus during Th17 differentiation. Various …

… IL-17 in infections. Lastly, we will look into the interaction of Th17 and Treg in autoimmune
diseases and inflammation: Th17 cells … Th17 cell differentiation is inhibited by transcriptional …

… T cells —Foxp3—, develop strong autoimmune disorders. Importantly, a severe form of
autoimmune … This underlines the importance of Foxp3 + Treg cells for controlling the immune …

… and fungi and in pathogenesis of autoimmune diseases. Selectively targeting the … 17. So
the next issue was how the production of IL-17 fits into our understanding of T cell differentiation…

… 17 cell differentiation and are thus produced by T H 17 cells … of T H 17 cells in various
human autoimmune conditions have … of the IL-23-IL-17 axis in autoimmune disorders. IL-17A is …

… in autoimmune disorders. … -17-producing Th17 cells in autoimmune responses and the
regulatory mechanisms for Th17 cell differentiation, a new paradigm of Th cell differentiation has …

… 17 cell differentiation from circulating, naive CD4 + T cells … 17 cells in autoimmune disorders,
but they do not exclude the participation of T H 1 cells in the pathogenesis of these diseases…

… encephalitis, IL-23 was shown to be required for the differentiation of T H 17 cells in vivo [7,8].
In addition, transforming growth factor-β and IL-6 are also important cytokines to induce …