… To determine if a similar approach would yield a novel model for Barrett's esophagus, we
subcloned a murine Cdx2 cDNA into a well-established K14/hGH transgenic expression vector …

… Barrett's esophagus. In this study, we use immunohistochemistry to detect Cdx2 in metaplastic
glandular epithelium of the esophagus … In addition, we examine Cdx2 protein expression …

… pgl-3-cdx2, cells transfected with plasmid containing the CDX2 promoter construct attached
to a luciferase reporter (-562 bp); pgl-3, cells transfected with pGL-3 plasmid vector lacking …

… ), and the incidence of EAC derived from Barrett's esophagus has steadily increased during
the previous 2 decades in most countries. 4 Barrett's esophagus affects ∼2% of the Western …

… matching normal squamous esophagus tissues (n = 39) collected from 19 patients with
Barrett's esophagus and 20 patients with esophageal adenocarcinoma. CDX2 protein expression …

… All control cases were Cdx2 negative. Strips of Alcian blue-positive nongoblet columnar …
were Cdx2 negative. In conclusion, Cdx2 is a highly sensitive marker for Barrett's esophagus…

… CDX-2 and a set of cytokeratins (CKs) as specific markers for BE as compared with normal
squamous esophageal … Immunohistochemistry (IHC) with specific antibodies against CDX-2, …

… Caudal homeobox gene 2 (CDX2) is a … induce CDX2 in esophageal and other epithelial
cell lines.24, 25, 26 The aim of this study was to test the hypothesis that exposure of esophageal …

… may enhance CDX2 expression in rat esophageal keratinocytes … bile acids and CDX2 in
human esophageal cells. The aim of … CDX2 mRNA expression in a variety of human esophageal …

… Cdx2 (Caudal-type homeobox 2) has been implicated as a master switch gene for intestine
and therefore for Barrett's … for the role of Cdx2 in the development of Barrett's metaplasia. …