In this review we summarize recent major advances in our understanding on the molecular
mechanisms, mediators, and biomarkers of acute lung injury (ALI) and alveolar-capillary …

… TNF can also directly increase endothelial permeability in pulmonary artery endothelial cells,
by means of destabilizing microtubules, which in turn induces barrier dysfunction in a RhoA/…

… to mortality in patients with acute lung injury and the acute respiratory … lung injury is
incompletely understood; however, both clinical and experimental ventilator-attributable lung injury …

… -H1 release, and the resulting activation of inflammatory signaling and barrier dysfunction
in pulmonary ECs, and evaluated the role of GEF-H1 in the LPS-induced lung injury in vivo. …

… The results showed that YPFS administration alleviated lung injury and suppressed the …
on lung injury in LPS-challenged mice by H&E staining. As illustrated in Fig. 6J, the lung tissues …

… barrier function and that LPS exposure inhibits AMPK, thereby contributing to endothelial
barrier dysfunction and lung injury… -induced endothelial barrier dysfunction and lung injury. LPS …

… between bacterial toxins and arginase during acute lung injury and will as such address
the role of arginase in bacterial toxin-induced pulmonary endothelial barrier dysfunction. …

… Therefore, stable pulmonary epithelial barrier might serve as a potential therapeutic … lung
injury with hemorrhage, edema, thickened alveolar wall and inflammatory cell infiltration in lung …

… lung injury or aggravate the original lung injury, resulting in ventilator-induced acute lung
injury (… , these conditions are all biological injuries in nature and are primarily characterized by …

… lung EC barrier preservation and reduce inflammation in acute lung injury (ALI), and effective
barrier-… Oxidative stress contributes to lung injury and barrier dysfunction via microtubule …