… in aging rat renal tissues, consistent with these data. Deficiency and dysfunction in autophagy
… the role of autophagy in the onset and development of kidney aging and kidney disease …

… of autophagy was significantly reduced in aging rat brain, and ICA intervention can increase
autophagy … neuronal dysfunction mainly through improve basal autophagy level in aging rat. …

… decrease in basal autophagy in cardiomyocytes is a significant contributor to aging-related …
The AMPK/mTOR/ULK1 signaling pathway is a key target for regulating autophagy. SPJ has …

… rat islets decreased gradually with aging. LC3-II puncta formation was significantly reduced
in 24-month-old rats compared to 4- and 14-month-old rats … induces basal autophagy with no …

… rats. In conclusion, ICH causes more severe autophagy and neurological deficits in aged
rats. … The ratio of LC3-II to LC3-I in the ipsilateral basal ganglia of aging rats was much higher …

… Basal oxygen and sugar consumption are quite constant in … ; thus, the rate of aging and
longevity in any given species may … stimulation of autophagy retards the process of aging in rats. …

… rats, dietary anti-aging intervention preserved the juvenile amino acid and hormone regulation
of autophagy.… However, a second affect on autophagy, through modulating basal insulin …

… how autophagy is involved in kidney aging. Unexpectedly, the basal autophagic activity was
… In conclusion, we report that an age-dependent elevation in basal autophagy plays a crucial …

… Instead of hampering the function of β cells, the degradation of cellular components by basal
autophagy is essential for the maintenance of normal architecture and function of β cells [7,…

… from 16- to 18-hour-fasted rats. Cell suspension (10 6 cells/… –fed rats a significant decline
in the autophagic proteolysis of … –fed rats, no further decrease in basal autophagic proteolysis …