… However, during chronic inflammation, CRP can also aggregate in tissues to form amyloids
with complex fibrils that are found in many chronic inflammatory diseases (see below). …

… The hypothesis that lifetime inflammation has decreased in modern populations and that aging
… As an approach to testing the inflammation–aging hypothesis in modern populations, we …

… that resemble aging … biological systems. The main aim of this review is to analyze the role
of free radicals, which are by products of chronic inflammation, in carcinogenesis and aging…

… Aging is a biological process characterized by time-dependent, progressive, physiological
… , we highlight the role of chronic inflammation in these age-related inflammatory diseases. …

… become activated to secrete a wide variety of biological products resulting in tissue injury
and fibrosis characteristic of chronic inflammation. The humoral factors (chemical mediators) …

… biology of the age-related inflammation. Moreover, such studies may provide useful mechanistic
insights to develop therapeutic opportunities against inflammation in aging and in age-…

… Recent studies have shown that chronic inflammation contributes to pathological aging by
… interactions between inflammation and telomere biology in immunological aging. Indeed, …

… aging is associated with the development of a systemic state of low-grade chronic inflammation
(… Systems biology has helped in identifying the mediators and pathways involved in these …

… in Biological Age observed at chronological age 38 had accumulated over the past 12 y.
Our analysis shows that Biological Age can provide a summary of accumulated aging in cases …

… However, it does bear noting that the chronic inflammatory state our model posits would
likely have consequences for the way adaptive immune cells behave. In particular, there is …