… are significant “sensor/detector” molecular recognition elements in biological systems: they
confer stability on duplex DNA, contribute to unique properties of thermophilic proteins, and …

… It shows potent anticancer activity better than taxol.35, 36 It also has better pharmacological
properties such as improved water solubility, and acts at the microtubules. It enhances …

… biological-based therapies. The book is unique in providing molecular structures for all
anticancer … of action, structure–function relationships, and pharmacology. It also provides relevant …

… The AMP stability in biological fluids and anticancer … anticancer agents and we describe
their biological activity. In addition, we summarize the methods used to increase their anticancer …

… gap between the elementary medicinal chemistry textbooks and the … molecular basis of the
action of antitumor drugs. Because of the huge number of agents that show in vitro antitumor …

… a source of new biologically active molecular motifs with improved scope for drug discovery.
… In addition, considering the 126 small molecule anticancer drugs effectively available in the …

… of the drug development process. This chapter will highlight the unique aspects of anticancer
drug … success, the recent developments in molecular biology and an understanding of the …

… Jeon and Kim examined the antitumor activity of COS with different molecular weight
against S180 (sarcoma 180 solid) and U14 (uterine cervix carcinoma number 14) tumor cell-…

… Most of the potential novel molecular targets for anticancer drug discovery can be grouped
into the following categories: growth factor receptor tyrosine kinases (RTKs) and serine/…

… organic molecules that bind to the DNA molecule via intercalation, and exert their antitumor
… bind, have to be viewed as acceptor sites rather than true receptors, since their biological …