[HTML][HTML] Biological mechanisms of COVID-19 acute respiratory distress syndrome

MA Matthay, A Leligdowicz, KD Liu - American journal of respiratory …, 2020 - atsjournals.org
… Airway and alveolar biology during classical acute respiratory distress syndrome (ARDS)
and coronavirus disease (COVID-19) ARDS. The alveolar–interstitial–capillary unit is similarly …

[HTML][HTML] Acute respiratory distress syndrome

MA Matthay, RL Zemans, GA Zimmerman… - Nature reviews Disease …, 2019 - nature.com
… as a heterogenous syndrome, generating momentum to identify clinical and biological features
to … lung in ARDS, the pathophysiology of ARDS and the mechanisms of injury that lead to …

Biological therapies in the acute respiratory distress syndrome

AJ Boyle, JJ McNamee, DF McAuley - Expert Opinion on Biological …, 2014 - Taylor & Francis
… a biological therapy is defined as a therapy of biological origin, that is, not chemically synthetic.
We provide a summary of the biological … of the mechanisms underlying ARDS we identify …

Acute respiratory distress syndrome: causes, pathophysiology, and phenotypes

LDJ Bos, LB Ware - The Lancet, 2022 - thelancet.com
Mechanisms of ARDS include activation and dysregulation of multiple overlapping and …
and contributes to the clinical and biological heterogeneity of ARDS. Approaches to reduce …

[HTML][HTML] The acute respiratory distress syndrome: mechanisms and perspective therapeutic approaches

JN Gonzales, R Lucas, AD Verin - Austin journal of vascular …, 2015 - ncbi.nlm.nih.gov
Acute Respiratory Distress Syndrome (ARDS) is a severe lung inflammatory disorder with a
30–50% mortality. Sepsis and pneumonia are the leading causes of ARDS. On the cellular …

[HTML][HTML] Pathophysiology and biomarkers of acute respiratory distress syndrome

S Fujishima - Journal of intensive care, 2014 - Springer
… Increased vascular permeability in ARDS is the result of several independent mechanisms.
… Mutlu GM: Leptin promotes fibroproliferative acute respiratory distress syndrome by inhibiting …

Clinical and biological heterogeneity in acute respiratory distress syndrome: direct versus indirect lung injury

CM Shaver, JA Bastarache - Clinics in chest medicine, 2014 - chestmed.theclinics.com
Twenty years ago, the American-European Consensus Conference on ARDS emphasized
the complexity of the pathogenesis of acute respiratory distress syndrome (ARDS) and …

The basic science and molecular mechanisms of lung injury and acute respiratory distress syndrome

P Aranda-Valderrama, AM Kaynar - International anesthesiology …, 2018 - journals.lww.com
Acute respiratory distress syndrome (ARDS) is a … clinically into a syndrome of acute respiratory
failure that debuts … to severely impaired gas exchange, pulmonary edema, intrapulmonary …

[HTML][HTML] Pathogenesis of acute respiratory distress syndrome

LA Huppert, MA Matthay… - … respiratory and critical care …, 2019 - thieme-connect.com
… and physiologic mechanisms that cause ARDS to improve our … biologically active material
to host cells that have beneficial effects.[123] [124] Thus, there may be several mechanisms by …

[HTML][HTML] The acute respiratory distress syndrome

MA Matthay, LB Ware… - The Journal of clinical …, 2012 - Am Soc Clin Investig
… However, effects of S1P or synthetic S1P receptor agonists may depend on biologic context
(60) and … treatment, advancing our understanding of the mechanism of the disease (Table 1). …