[HTML][HTML] Biomarkers of cytokine storm as red flags for severe and fatal COVID-19 cases: A living systematic review and meta-analysis

AKG Melo, KM Milby, ALMA Caparroz, ACPN Pinto… - PloS one, 2021 - journals.plos.org
… This study concluded that the cytokine storm is associated with COVID-19 severity, likely
through increased pulmonary pathology, T cell depletion, and CD4+ T cell dysfunction. …

[HTML][HTML] Definition and validation of serum biomarkers for optimal differentiation of hyperferritinaemic cytokine storm conditions in children: a retrospective cohort study

C Kessel, N Fall, A Grom, W de Jager… - The Lancet …, 2021 - thelancet.com
Cytokine storm syndromes are life-threatening complications that can occur in children with
… We aimed to define and validate serum biomarker profiles that can differentiate between …

[HTML][HTML] Characterization of the cytokine storm reflects hyperinflammatory endothelial dysfunction in COVID-19

JT Sims, V Krishnan, CY Chang, SM Engle… - Journal of Allergy and …, 2021 - Elsevier
… , confirming reliability and reproducibility of our assays, we demonstrate that intervention
with baricitinib attenuates these circulating biomarkers associated with the cytokine storm. …

Point‐of‐care detection of cytokines in cytokine storm management and beyond: Significance and challenges

G Liu, C Jiang, X Lin, Y Yang - View, 2021 - Wiley Online Library
… As a result, no study has provided conclusive results indicating cytokines are biomarkers
for these diseases. To our knowledge, no cytokine has been approved to be biomarker for …

An intelligent graphene‐based biosensing device for cytokine storm syndrome biomarkers detection in human biofluids

Z Hao, Y Luo, C Huang, Z Wang, G Song, Y Pan… - Small, 2021 - Wiley Online Library
… Abnormal elevated levels of cytokines such as interferon (IFN), interleukin (IL), and tumor
necrosis factor (TNF), are considered as one of the prognosis biomarkers for indicating the …

[HTML][HTML] Description and analysis of cytokine storm in registered COVID-19 clinical trials: a systematic review

K Eljaaly, H Malibary, S Alsulami, M Albanji, M Badawi… - Pathogens, 2021 - mdpi.com
… changes in inflammatory biomarkers [4,6]. Therefore, the objective of this systematic review
was to describe the variability in identifying patients with cytokine storm in clinical trials of …

[PDF][PDF] Discrimination of COVID‐19 from inflammation‐induced cytokine storm syndromes using disease‐related blood biomarkers

C Kessel, R Vollenberg… - Arthritis & …, 2021 - Wiley Online Library
cytokine storm conditions as defined by clinical and laboratory criteria. Therefore, in this study,
we analyzed serum biomarker … or MAS (as classic cytokine storm syndromes), and found …

IL6 at the center of cytokine storm: Circulating inflammation mediators as biomarkers in hospitalized COVID‐19 patients

HM Elbadawy, A Khattab, DS El‐Agamy… - Journal of Clinical …, 2023 - Wiley Online Library
… intensified inflammatory response known as the cytokine storm. Candidate inflammatory
cytokines can serve as new biomarkers for the management of hospitalized COVID-19 patients. …

Distinct patterns of blood cytokines beyond a cytokine storm predict mortality in COVID-19

C Herr, S Mang, B Mozafari, K Guenther… - Journal of …, 2021 - Taylor & Francis
… The aim of the present study was to identify clinically relevant serum biomarkers from a
large … We measured serum levels of a large panel of cytokines, chemokines, acute phase …

[HTML][HTML] Cytokine storm

DC Fajgenbaum, CH June - New England Journal of Medicine, 2020 - Mass Medical Soc
… liver function, should be performed in all suspected cases of cytokine storm. Measurements
of inflammatory acute-phase biomarkers, such as CRP and ferritin, and blood counts should …