… The purified HRPO/anti-HRPO bispecific antibody immune complex could be directly used
… arm of the bispecific antibody binds specifically to a target, such as SARS-CoV antigen, or a …

… Although several neutralizing antibodies were authorized for … natural antibodies are vulnerable
to SARS-CoV-2 Spike mutation. Here, we describe the screen of a panel of SARS-CoV-2 …

… antibodies (mAbs) that efficiently neutralize SARS-CoV-2 … of Abs in SARS-CoV-2 immunity,
we expressed a SARS-CoV-2 … H4 subtypes were able to neutralize SARS-CoV-2. However, …

… new mechanisms of action beyond monospecific and bispecific antibodies (bsAbs) that can
… bnAb targeting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), BAT2022, …

… providing a rich toolbox of modular parts for bispecific development. Yet, this toolbox remains
… antibody discovery and bispecific iteration in order to rapidly address emerging SARS-CoV-…

… S6, F and H), we produced a bispecific antibody that includes the moieties of both … Efficacy
of the bispecific antibody was confirmed against ancestral and Omicron SARS-CoV-2 in vitro …

… is bispecific engineering by connecting antibodies targeting … antibodies function
independently, bispecific antibodies … bispecific nanobody targeting two relatively conserved SARS…

… Design of bispecific antibodies and neutralization of Wuhan-1 SARS-… of neutralization for
both SARS-CoV-1 and SARS-CoV-2 PSVs, we choose to construct bispecific designs around …

… anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV)/horseradish peroxidase
(… HRPO to eliminate the homodimeric monospecific anti-SARS-CoV (Table 1). Protein A and …

… monoclonal antibody therapies. Here we report a tetravalent bispecific antibody ISH0339,
as a … Methods: We report here the making of ISH0339, a novel tetravalent bispecific antibody …