Bloodbrain barrier dysfunction as a cause and consequence of Alzheimer's disease

MA Erickson, WA Banks - Journal of Cerebral Blood Flow & …, 2013 - journals.sagepub.com
… We will specifically focus on three aspects of BBB dysfunction: disruption, perturbation of …
of BBB dysfunction. From the results discussed herein, we conclude that BBB dysfunction

Bloodbrain barrier dysfunction and recovery

AG De Boer, PJ Gaillard - Journal of Neural Transmission, 2006 - Springer
… In this paper we discuss the importance of the bloodbrain barrier (BBB) as an interface
between blood and brain. … The bloodbrain barrier (BBB) is the interface between blood and …

Blood-brain barrier dysfunction in disorders of the developing brain

R Moretti, J Pansiot, D Bettati, N Strazielle… - Frontiers in …, 2015 - frontiersin.org
brain injury. We present an overview of current knowledge about BBB dysfunction in the
developing brain during acute and chronic insults, along with clinical and experimental data. …

Alzheimer's disease: a matter of bloodbrain barrier dysfunction?

A Montagne, Z Zhao, BV Zlokovic - Journal of Experimental Medicine, 2017 - rupress.org
… human studies demonstrating BBB breakdown and dysfunction in AD and examine BBB …
of blood-to-brain vascular integrity. We discuss the role of BBB breakdown and dysfunction in …

[HTML][HTML] Diabetes mellitus and blood-brain barrier dysfunction: an overview

S Prasad, RK Sajja, P Naik… - Journal of …, 2014 - ncbi.nlm.nih.gov
A host of diabetes-related insults to the central nervous system (CNS) have been clearly
documented in type-1 and-2 diabetic patients as well as experimental animal models. These …

Blood-brain barrier dysfunction and the pathogenesis of Alzheimer's disease

Y Yamazaki, T Kanekiyo - International journal of molecular sciences, 2017 - mdpi.com
Brain capillary endothelial cells form the blood-brain barrier (… exchange between the
blood flow and brain parenchyma, … Thus, dysfunction of the BBB is likely involved in the …

APOE4 leads to bloodbrain barrier dysfunction predicting cognitive decline

A Montagne, DA Nation, AP Sagare, G Barisano… - Nature, 2020 - nature.com
… Recent studies have suggested that breakdown of the bloodbrain barrier (BBB) is an early
biomarker of human cognitive dysfunction 7 , including the early clinical stages of Alzheimer’…

Peripheral markers of brain damage and blood-brain barrier dysfunction

N Marchi, P Rasmussen, M Kapural… - Restorative …, 2003 - content.iospress.com
bloodbrain barrier integrity, we measured both NSE and S100β in the serum of patients
with primary central nervous system lymphoma who underwent iatrogenic blood-brain barrier

Bloodbrain barrier dysfunction in parkinsonian midbrain in vivo

R Kortekaas, KL Leenders… - Annals of …, 2005 - Wiley Online Library
… which includes specialized proteins on the inside of blood vessels in the brain. These act as
… in the bloodbrain barrier. We used positron emission tomography to measure brain uptake …

Bloodbrain barrier dysfunction in brain diseases: Clinical experience

K Schoknecht, H Shalev - Epilepsia, 2012 - Wiley Online Library
bloodbrain barrier dysfunction are diverse and may range from physical endothelial damage
in traumatic brain injury … Clinically, bloodbrain barrier dysfunction is often detected using …